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Here are 3 abstracts that caught my eye on Day 2 at ACR25. Notably these have takeaway messages that should support your current practices.
Stress Raises the Risk of Psoriasis

New longitudinal research reveals that severe stress caused by changes in family s

Dr. John Cush RheumNow

9 months 1 week ago
Stress Raises the Risk of Psoriasis New longitudinal research reveals that severe stress caused by changes in family structure like divorce or separation experienced during the first year of life may triple the risk of developing psoriasis later in life. https://t.co/TSXoQKjRPN
After a full day at the Chicago Convention center the RheumNow faculty have posted some of their favorite reports included these that they labeled as being the "best' of day 2.
CAR T-cells have been a revolutionary development in rheumatology. We have seen a population of patients with severe refractory autoimmune conditions almost overnight presented with the prospect of not just improvement, but of a cure.
A growing arsenal of therapeutic targets in psoriatic arthritis (PsA) has enhanced the landscape of treatment in patients with this disease.
Off the Shelf: CAR-T
In a retrospective study of TAK patients, ~about 1/3 developed new lesions on imaging over time

Most lesions:
- stenoti

Brian Jaros, MD Dr_Brian_MD

9 months 1 week ago
In a retrospective study of TAK patients, ~about 1/3 developed new lesions on imaging over time Most lesions: - stenotic - L carotid - Abdominal aorta - SMA 50% of the 1/3 = 2 or more lesions Serial imaging is crucial! @RheumNow #ACR25 Abst 1631
How does DADA2 present?

Ten studies provided data on a total 225 patients

1) skin findings
2) fever
3) stroke
4) cyto

Brian Jaros, MD Dr_Brian_MD

9 months 1 week ago
How does DADA2 present? Ten studies provided data on a total 225 patients 1) skin findings 2) fever 3) stroke 4) cytopenias @RheumNow #ACR25 Abst 1615 https://t.co/xZuTk6YFdJ
New Approaches to Therapy in PsA
PET and histologic discordance in aortitis

Of 5 aortitis patients who had PET/CT prior to aortic surgery with path, onl

Brian Jaros, MD Dr_Brian_MD

9 months 1 week ago
PET and histologic discordance in aortitis Of 5 aortitis patients who had PET/CT prior to aortic surgery with path, only 1 showed concordance (neg PET, neg biopsy) 4/5 patients had inflammatory biopsy with neg PET Small # but PET is not perfect! @RheumNow #ACR25 Abst 1620
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