Dr. John Cush RheumNow
7 years 7 months ago
A study of 2,369 patients with fibromyalgia showed the mean time from initial complaint to diagnosis was 6.42 years. Comorbidity, younger patient, and older physician age were associated with longer time to diagnosis. https://t.co/mHGIR7C4PW
Dr. John Cush RheumNow
7 years 7 months ago
QD Clinic - Five Leflunomide Pearls | from RheumNow https://t.co/A4dwd0eTQ9
A systematic review has shown that TNF inhibitors (TNFi) are equaled in efficacy by other biologic agents (ustekinumab, secukinumab, and ixekizumab) in psoriatic arthritis (PsA) patients with in dactylitis and enthesitis.
Data from the longitudinal Tromsø Lupus Cohort study has shown that lupus patients who achieve a Lupus Low Disease Activity State (LLDAS‐50) were shown to have significantly less severe damage, and a reduction in mortality.
This was a population‐based study of SLE patients in the northern‐most counties of Norway.
QD Clinic - Five Leflunomide Pearls
Insights on Leflunomide use and management
Dr. John Cush RheumNow
7 years 7 months ago
Very 1st case I heard on Rheum Rounds 1984 was on Moya-Moya. A review of Delay & mis-Dx in 38% of 192 pts - time to Dx=mean 5.28 yrs; usually misDx as cerebral vasculitis (31%), stroke(30%) & MS(3.6%). Moyamoya is progressive, occlusive cerebrovascular Dz https://t.co/cxu7s3snEJ
Dr. John Cush RheumNow
7 years 7 months ago
Pt with a history of gout. Acute onset of pain at 1st MTP joint. Ultrasound shows 1st MTP Synovitis. Synovial thickening with hypervascularity is noted on the dorsal aspect of 1st metatarsophalangeal joint. https://t.co/BH4C56Yerq
Dr. John Cush RheumNow
7 years 7 months ago
From CreakyJoints- 20 Things pts wish their Rheums Knew: 1 Fix the Vocab, 2 Dont rush me, 3 Dont sugarcoat, 4 Realistic diet, 5 Listen to me, 6 Dont judge me, 7 Flares last longer than you think, 8 Do a mental check up; AND MORE https://t.co/TuKIn86RNv
Patients with moderate-to-severe plaque psoriasis attained durable complete and near-complete responses for more than a year with a dual inhibitor of interleukin (IL)-17, data from a randomized trial showed.
Dr. John Cush RheumNow
7 years 7 months ago
Surprising Resignation by FDA Commissioner Scott Gottlieb - cites need for more family. Does so after bring vaping, costs and opioids into the spotlight. Could Rheumatologist Janet Woodcock be the next candidate? https://t.co/FnL7Wn0jnT
Dr. John Cush RheumNow
7 years 7 months ago
From PRECISION study (high risk CV pts), Solomon et al shows a toxicity score (age, sex,CV hx,HTN, DM, tobacco, statins, creatinine, HCt, RA v OA) can predict risk of CV events: ~5% at low risk (<1%), 69% at intermediate risk (1- 4%), 27% high risk (>4%). https://t.co/nMXBMdaxvE
QD Clinic - When it’s not Rheumatoid Arthritis
A 2nd Opinion Consult for RA - But I Don't Think it's RA
Say a conference in your field was just announced. You think you "should" go, and you know you'll be choosing from many presentation opportunities that feature the latest research — which you want to know about. And you'll get to hang with like minds and talk about things that matter.
Dr. John Cush RheumNow
7 years 7 months ago
Could Metformin be adjunctive in gout? MSU crystals induce mTOR signalling in monocytes; sam pathway strongly implicated in CV & metabolic disease. Ex vivo studies show high higher mTOR expression gout - downreg by metformin or rapamycin https://t.co/qA3a9WCUq8
Dr. John Cush RheumNow
7 years 7 months ago
An Internet survey of 320 physician-diagnosed #gout pts finds that 23% diagnosed as having a sleep disorder (sleep apnea, 17%). Their mean sleep time was 6.7 h per night; 86% reported snoring during sleep and 2/3 reported feeling sleepy during the day https://t.co/7DiuZOM1aw
