The ‘dark’ side of #Hidradenitis #suppurativa 👇 Smell of leaking lesions #HS ⬆️skin folds, buttock, axilla, also thighs, neck ⬆️depression @RheumNow #RNL2025 ‘ If pt doesn’t get in gown then not ready for systemic #Rx!’ Jennifer Clay #ClinicalPearl https://t.co/tZzz5tielt

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-HS ttx👇 1. Lifestyle changes: smoking cessation, obesity. 2. Management of comorbidities. 3. 🔍HS- related autoimmune disorders. 4. FDA approved biologics: -Adalimumab (PIONEER 1&2) -Secukinumab (SUNRISE, SUNSHINE) -Bimekizumab (BE HEARD 1&2) "Theres no such… https://t.co/G5Voxrm3Kt https://t.co/dLGtoFZMd1

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1/3 of #axial #PsA 👇 No #SI joint changes , only #axial ⁦@RheumNow⁩ #RNL2025 Catherine Blackwell #ClinicalPearl https://t.co/YmoipL1bME

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Pregnancy is 🔥 inflammatory Hard to interpret MRI of SI joints in setting of pregnancy Ideally, don't score MRI during pregnancy or 1 year afterwards, would be affected by the pregnancy If needed for clinical eval, focus on structural lesions like erosions #RNL2025 @RheumNow

Full read review and overview of Fibromyalgia - manifestations, pathophysiology, treatments and guidelines. Multidisciplinary, patient-centered treatment should includes a combination of pharmacological and nonpharmacological options. https://t.co/x4OVeQ5RJz https://t.co/i1fD6XQbnx

• Fibromyalgia: Understanding, Diagnosis and Modern Approaches to Treatment

P2 Trial: DEU in PsA Encouraging results for DCV 6 and 12 mg qd. ACR20 63% for DCV 12 mg (p=0.0004) Not yet FDA approved for PsA, only PsO Pending P3 P2: DEU in SLE - PAISLEY Improved SRI(4), CLASI-50 at w32 Merola #RNL2025 @RheumNow https://t.co/RV7OPaZWjx

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Combination therapy in PsA . Regulatory and reimbursement issues may inhibit such strategies (and potential adverse event concerns) but anecdotal evidence would suggest a role in difficult to treat cases. @RheumNow #RNL2025 https://t.co/IIoUiJyP95

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MDA5 + Pts with #ILD in #dermatomyositis can improve! ⁦@RheumNow⁩ ⁦@ACRheum⁩ #RNL2025 Data from Christina Charles-Schoeman #ClinicalPearl Her pearls 👇 #DM is a #vascular #disease #CK is not reliable in chronic DM Neg Abs don’t r/o #myositis https://t.co/hxomz70aq5

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#RNL2025 @RheumNow Dermatomyositis is VASCULAR disease -IVIG may help DM by blocking complement deposition on endomysial capillaries -CK levels not reliable Pruritus common in up to 86% of DM patients Dr. Charles-Schoeman, UCLA

#RNL2025 @RheumNow JAKi in DM: @JuliePaikMD- 10 DM pts open label on JAKi. 7/10 improved from mod/severe to mild. In 96wk extension, 6 of 7 continued response 145 case reports for tofa, bari, ruxolitinib. Role in helping calcinosis? Pruritu? Brepocitinib (JAK1/TYK2i) study

Pearls on Dermatomyositis: -Negative myomarker does not r/o DM -Pruritus can be a skin manifestation in DM🚨 -Combination therapy upfront =achieve faster remission -Evidence for JAK inhibitors in management -JAKis seem to have good effect in DM-calcinosis -In DM with rapidly… https://t.co/J3iiDa6ph7 https://t.co/0WTHKa97bt

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Importance of not over-relying on lab tests. We can test for what we can test for, but this is not comprehensive. For me in clinical practice - Postive antibodies can confirm diagnosis of DM but negative cannot exclude it. @RheumNow #RNL2025 https://t.co/Kyfzne4BSD

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Do you want to know a secret? @drcharitydean shares that doctors are wired in the same way that #AI is built. We understand the layers of complexity & are best equipped to partner with AI. @rheumnow #RNL2025

"Treat for the most likely, mitigate for the catastrophic" @drcharitydean (my hero!). Read her story in "Premonition" by Michael Lewis. She served an impt role in the COVID19 pandemic as a public health officer for CA. Her lecture is on re-inventing yourself. @rheumnow #RNL2025 https://t.co/3ZWgClzez1

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#HOT #topic Will #Rx of #PsO PREVENT onset of #PsA Well, maybe 🤔 Alexis R Ogdie ⁦@RheumNow⁩ #RNL2025 70% of #psoriatic #arthritis is preceded by #psoriasis Still a bit of a debate re prevention of PsA https://t.co/7bce8kcjdr

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