Different types of IFNs have different actions and signaling pathways. Dr. Crow #RNL2025 @rheumnow https://t.co/1lJFwlhO92

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Some pearls from RA POD at #RNL2025 -What do rheumatologists want from AI: Right drug for right patient, improving documenting in less time and possibly include multimorbidity management? -Utilize AI as enhancer not replacement of the physician. AI must be trained well in a… https://t.co/9YNmeVx4t6

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ACR Commends Legislation Addressing Harmful Medicare Payment Cuts to Physicians The ACR applauded the bipartisan introduction of the Medicare Patient Access and Practice Stabilization Act of 2025, legislation to fully offset the harmful 2.8% cut in the Medicare Physician Fee… https://t.co/UqBbAyHLm0 https://t.co/3DJN7ojMHl

OK this is ‘HOT’ App on phone for a 👇 #thermal #camera Of hands 🙌 If #hot➡️ flare of #inflammatory #arthritis And call for a #follow up apt If not — then not a flare #AI #artificial #intelligence #rheumatoid #arthritis @RheumNow #RNL25 Jeff Curtis AI in #rheum

How can AI be useful for RA pts and rheumatologists? -AI models have the potential for improving diagnosis, management and outcomes in RA pts. -Can also improve efficiency and clinic workflow. -Not so perfect as it sounds (hallucinations, limited accuracy) #RNL2025 @RheumNow https://t.co/44LUHQ1KPf

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AI models require good Positive Predictive Value (PPV) But: PPV decreases as prevalence decreases - In choosing a successful biologic: Harder to predict more challenging patients (multiple failures, co-morbidities, etc) - ACR50 non-response is higher J Curtis @RheumNow #RNL2025 https://t.co/SdJ0FHVuSC

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#AI can help with Value Based Care…a year in remission for RA will save a lot of money. @RADoctor @rheumnow #RNL2025 https://t.co/rUpeMrDHZf

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Late onset RA (LORA) aka RA diagnosed at an older age — pts have higher inflammatory markers, presents like PMR; they also have polypharmacy, comorbidities, frailty, etc that can complicate management @UnaMakris #RNL2025 @RheumNow #GeriRheum https://t.co/zqEcyg2ejw

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@UnaMakris #RNL25 @RheumNow Older patients w RA 1/3 of pts onset >60-65 - More acute onset, more systemic, more PMR-like, larger jts - Higher IL-6, lower TNF-a, less RF, higher ESR -Co-morbidities, polypharmacy, cognition, depression Age does not equal frailty, but does correlate https://t.co/5qb60WyKkP

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Rheumatic diseases become more common with aging, dramatically so. @UnaMakris @RheumNow #RNL2025 https://t.co/EXKHP9ufUj

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Can #AI help us determine the 👇 Right drug At Right time Pipe dream? Or to use #artificial #intelligence term ➡️ a #hallucination? garbage in ➡️➡️garbage out Most predictions of drug response are same: multimorbid multiRx failures Nonadherent poverty #RNL25 @RheumNow https://t.co/70SRp8BnCl

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#RNL2025 is underway! https://t.co/VDEvK70Qg5

Such an important topic from @UnaMakris . The intersection of aging with our rheumatic disease processes is a crucial area. @RheumNow @RNL2025 https://t.co/n0Kx559g9e

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Are your patients aging with RA, or are they diagnosed with Late Onset RA (LORA)? -LORA pts tend to present acutely -High inflammatory markers~PMR Like -Seronegative/Decreased titers of RF/CCP @UnaMakris #RNL2025 @RheumNow https://t.co/aOCwb3lHef

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J Curtis #RNL2025 @RheumNow AI Will Not Replace You - AI cannot replace human interaction, examination, procedures, interpreting guidelines for an individual, providing empathy, and facilitate good patient education Will become a tool... but not a replacement to a good clinician https://t.co/qPcNOjWepi

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