While many adult rheumatologists are able to lessen or withdraw DMARD and biologic therapy in adults, little is known about the success of this practice in pediatric rheumatology clinics. Reiff and coworkers have reported on their retrospective observational study of 335 patients with polyarticular JIA or enthesitis-related arthritis and analyzed the frequence of clinically inactive disease (CID) and flare free survival (FFS) off medications.
The global knee implants market was USD 8.4 billion in 2011, and it's forecasted to reach USD 15 billion in 2018, with compound annual growth rate of 8.64% during 2011 to 2018. The U.S. and Europe are the two big markets for knee implants, and both the countries enjoy more than 70% market share of global knee implants.
The diagnosis of chronic lung disease in patients with systemic sclerosis may be difficult because of atypical symptoms, variable evolution and limitations of current classification criteria for a definite diagnosis. Nevertheless, diagnosis is necessary as patients with SSc-ILD have a poorer prognosis than those with SSc without pulmonary involvement.
A 12-week, phase III, non-inferiority, randomized clinical trial of tofacitinib, etanercept or placebo was conducted in 1106 patients with plaque psoriasis.
A CDC report shows comorbid conditions exist in 73.1% of all arthritis patients. Based on NHIS survey data, the number of patients with 2 or more comorbid conditions has increased from 21.8% in 2001 to 25.5% in 2012. Most affected were older adults (≥65 years), women, whites or blacks, overweight or obese adults, and current or former smokers. Modifiable lifestyle behavior factors, such as poor diet, physical ina
NHANES data shows eczema is associated with a higher rate of fractures and osteoporosis. Of the nearly 5,000 people included in the study, seven percent reported a diagnosis of eczema.
Saavedrra and coworkers studied 178 lupus pregnancies and compared outcomes in the 87 azathioprine exposed compared to the 91 who were not exposed. There were no differences between groups with regard to fetal outcomes. No major congenital malformatons were noted.
Dr. Angus Worthing writes of patient angst over rising copays. Expensive specialty medications are the frequent target of "sharing" the rising costs of medications and making them the patients responsibility and not the insurers.
If you’re going to spend 10-20% of your clinic hours examining and caring for 28 or 68 or 360 joints – it may be instructive to own up to those joints we excel at and take note of the ones we avoid, despise or struggle with.
Adult-onset Still's posses a interestng and diagnostic challeng when encountered. Here are 5 tips to improve your diagnostic acumen for this febrile disorder.
The DRESS syndrome is a rare and sometimes catastrophic disorder resulting from specific drug exposures, including allopurinol, minocycline, INH, anticonvulsants or retroviral agents.
I was recently asked, “what is the best kind of arthritis to have?” My response is based on diagnosibility, treatability and safety of necessary treatment.
Drug efficacy is swiftly proven in phase II and III trials. Yet drug safety requires time, wider exposure, physician education and patient acceptance to be fully established.
Dalbeth and coworkers studied 92 patients with gout and using DECT scanning have shown those with urate deposition on DECT were 8.5-fold more likely to have erosive disease on plain radiographs. Of the 920 joints assessed by DECT, 16.6% of them had dual-energy CT (DECT) urate deposition. These results suggest urate crystal deposition is integral in developing structural joint damage in gout.
Researchers from the University of Manchester investigated self-reported adherence to biologic treatment in RA and found that 41% of patients were non-adherent to adalimumab therapy at least once, and 23% were nonadherent overall. http://bit.ly/1KA29LI
