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Lots of lupus research and the New ACR Guidelines on Lupus Nephritis management were presented today. These and other highlights as featured on our Twitter (X) feed from ACR24 in Washington, DC.
Potential Impact of Weight Loss Drugs in Rheumatic Diseases

Dr. Arthur Kavanaugh highlights a session regarding weight

Dr. John Cush RheumNow

1 year 8 months ago
Potential Impact of Weight Loss Drugs in Rheumatic Diseases Dr. Arthur Kavanaugh highlights a session regarding weight loss and improvement in disease outcomes, specific weight loss drugs (SGL-2 and GLP-1), along with downsides when patients stop these medications. Reporting… https://t.co/Ilu2FXK2xi https://t.co/7CKSnfuey4
A#2651
Vasculitis w VEXAS
81 men, median age 67 - 27% had evid of vasculitis, variable size vessel

22% SVV- 17/18 cutan

Eric Dein ericdeinmd

1 year 8 months ago
A#2651 Vasculitis w VEXAS 81 men, median age 67 - 27% had evid of vasculitis, variable size vessel 22% SVV- 17/18 cutaneous, one peritubular capillaritis on renal bx 2.5% MVV (2 cutan), LVV (2 carotid thickening, 1 had +TA bx), ANCA+ @RheumNow #ACR24 https://t.co/puablIBLCP
What factors are assoc with uptake of newer meds in RA?

➡️Incr use of b/tsDMARDs over 10yrs
➡️Use of newer drug

Mrinalini Dey DrMiniDey

1 year 8 months ago
What factors are assoc with uptake of newer meds in RA? ➡️Incr use of b/tsDMARDs over 10yrs ➡️Use of newer drugs lower in older ppl, socioeconomic deprived & Asian/Black ppl Could this indicate disparities in access to meds? How can we best address this? Ab2608 #ACR24 @RheumNow
How often do you ask about #fatigue, #depression & #anxiety in pts with RMDs?

Study of >1000 pts found anxiety s

Mrinalini Dey DrMiniDey

1 year 8 months ago
How often do you ask about #fatigue, #depression & #anxiety in pts with RMDs? Study of >1000 pts found anxiety symptoms in 1/3 pts and significant association between fatigue & anxiety and depression Highlights importance of regular review of MH symptoms Ab2657 #ACR24 @RheumNow https://t.co/0zMOMybrCI
A#2652
NEWTON study 🇫🇷 Retrosp cohort

51% relapse. Median @8.7 mos, dose 9mg pred
Rf: limb art involv- HR 1.9
Pre

Eric Dein ericdeinmd

1 year 8 months ago
A#2652 NEWTON study 🇫🇷 Retrosp cohort 51% relapse. Median @8.7 mos, dose 9mg pred Rf: limb art involv- HR 1.9 Pred taper speed not risk for relapse Most relapse -> incr GCs Toci 1/3 at dx, 50% stopped -61% d/c due to remission, 39% SEs -1/3 relapse after d/c @RheumNow #ACR24 https://t.co/NP0wieDmvo
Peyrac et al. 211 GCA. Relapse in 52% at median 261 days (so 1st year). 83% on GCs at relapse, median dose 6.5mg pred. 3

Richard Conway RichardPAConway

1 year 8 months ago
Peyrac et al. 211 GCA. Relapse in 52% at median 261 days (so 1st year). 83% on GCs at relapse, median dose 6.5mg pred. 36% relapse post-toc discontinuation, at median 133 days. 64% no relapse when toc stopped, at median 511 days @RheumNow #ACR24 Abstr#2652 https://t.co/NqtdDNGGoc https://t.co/mXD8x7O6Ww
What is the effect of cs/bDMARDs on weight in #PsA?

⬇️Weight loss seen with:
IL17i
IL23i
csDMARDs

⬆️Weight gai

Mrinalini Dey DrMiniDey

1 year 8 months ago
What is the effect of cs/bDMARDs on weight in #PsA? ⬇️Weight loss seen with: IL17i IL23i csDMARDs ⬆️Weight gain seen with: TNFi IL12/23i Important to consider #comorbidity & #BMI in management decisions in PsA Ab2639 #ACR24 @RheumNow
A New ACR

Dr. Jack Cush highlights a few notable changes to the ACR meeting format this year, and offers pointers on th

Dr. John Cush RheumNow

1 year 8 months ago
A New ACR Dr. Jack Cush highlights a few notable changes to the ACR meeting format this year, and offers pointers on the best way to stay informed and abreast of reporting from the #ACR24 Convergence meeting in Washington, DC. https://t.co/YmI6s1TanV https://t.co/hsByGEBtnz
A#2648
PET for GCA
Delayed imaging at 180 min improve dx performance for pts on GCs
Optimal PET w/in 3 days of GC, most

Eric Dein ericdeinmd

1 year 8 months ago
A#2648 PET for GCA Delayed imaging at 180 min improve dx performance for pts on GCs Optimal PET w/in 3 days of GC, most patients unable to do w/in that window Delay has sensitivity 92% even on prednisone - may be good tool for pts unable to get early PET/CT #ACR24 @RheumNow https://t.co/kxpNfRqkGN
Study by Maria Dall'Era et al. compared voclosporin-based triple immunosuppressive therapy with high-dose GC in active l

Antoni Chan MD (Prof) synovialjoints

1 year 8 months ago
Study by Maria Dall'Era et al. compared voclosporin-based triple immunosuppressive therapy with high-dose GC in active lupus nephritis. - Fewer adverse events in the voclosporin group, despite a higher incidence of specific issues like decreased GFR and hypertension. - 25%… https://t.co/ToRu2rdErC https://t.co/uUXzNNuLDb
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