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πŸ’Š After TNFi failure in axSpA, switch to IL-17Ai or cycle TNFi?

ROC-SpA (Phase 4 RCT, n=300):

NO difference: ASAS

Nelly ZIADE πŸ€ Nellziade

1 month 3 weeks ago
πŸ’Š After TNFi failure in axSpA, switch to IL-17Ai or cycle TNFi? ROC-SpA (Phase 4 RCT, n=300): NO difference: ASAS40 15.2% vs 14.5% at week 24 #OP0235 #EULAR2026 @RheumNow https://t.co/45gisWiuoM
πŸ”¬ Can filgotinib improve axSpA?

OLINGUITO (Phase 3 RCT, n=495):

YES! ASAS40 39.5% vs 21% (r-axSpA) at week 16

#O

Nelly ZIADE πŸ€ Nellziade

1 month 3 weeks ago
πŸ”¬ Can filgotinib improve axSpA? OLINGUITO (Phase 3 RCT, n=495): YES! ASAS40 39.5% vs 21% (r-axSpA) at week 16 #OP0234 #EULAR2026 @RheumNow https://t.co/0vj2KqSS1b
βš–οΈ Does BMI outrank treatment in early PsA outcomes?

YES - SPEED trial AI analysis:
BMI #1 predictor of PASDAS at

Nelly ZIADE πŸ€ Nellziade

1 month 3 weeks ago
βš–οΈ Does BMI outrank treatment in early PsA outcomes? YES - SPEED trial AI analysis: BMI #1 predictor of PASDAS at 1yr in 192pts #OP0187 #EULAR2026 @RheumNow https://t.co/9cZG7AWau2
Good news! #Survival in #SLE is improving
#SLR of #lupus publications over time in 233 publications

Bad news - still

Janet Pope Janetbirdope

1 month 3 weeks ago
Good news! #Survival in #SLE is improving #SLR of #lupus publications over time in 233 publications Bad news - still a mortality gap! #EULAR2026 @RheumNow @eular_org ABST#POS0684 https://t.co/PVmQI2duYS
πŸ’‰ Does bimekizumab work in real-world PsA?

YES - EuroSpA: 76% retention at 6months
46% DAPSA LDA in 787pts across 1

Nelly ZIADE πŸ€ Nellziade

1 month 3 weeks ago
πŸ’‰ Does bimekizumab work in real-world PsA? YES - EuroSpA: 76% retention at 6months 46% DAPSA LDA in 787pts across 12 registries #OP0185 #EULAR2026 @RheumNow https://t.co/TXS3r9mZXB
🧲 Does GUS+GOL combo beat GUS alone on MRI in PsA?

YES for joints - AFFINITY Phase 2a RCT: greater MRI inflammation

Nelly ZIADE πŸ€ Nellziade

1 month 3 weeks ago
🧲 Does GUS+GOL combo beat GUS alone on MRI in PsA? YES for joints - AFFINITY Phase 2a RCT: greater MRI inflammation reduction in 91pts #OP0186 #EULAR2026 @RheumNow https://t.co/9eIS6lh7WN
Sustained remission in #SLE at 5 yrs w CAR-T
8 severe SLE patients treated with
autologous CD19-CAR T cells
(Zorpocel; M

Janet Pope Janetbirdope

1 month 3 weeks ago
Sustained remission in #SLE at 5 yrs w CAR-T 8 severe SLE patients treated with autologous CD19-CAR T cells (Zorpocel; Miltenyi Biomedicine) #antiDNA and #SLEDAI #antiSm ➑️prolonged suppression Big ? - how long will it work for Impressive! @RheumNow #EULAR2026 #EULARbest #729 https://t.co/8iOSImX3w6
🧬 Do biomarkers predict #zasocitinib response in PsA?

YES: TYK2/IL-17 pathway markers predict ACR20 in 290pts Phase

Nelly ZIADE πŸ€ Nellziade

1 month 3 weeks ago
🧬 Do biomarkers predict #zasocitinib response in PsA? YES: TYK2/IL-17 pathway markers predict ACR20 in 290pts Phase 2b RCT #OP0184 #EULAR2026 @RheumNow https://t.co/AVlyrauI5q
πŸ”Ž Can US predict PsA progression from psoriasis?

YES: synovio-entheseal inflammation predicts progression in 183pts

Nelly ZIADE πŸ€ Nellziade

1 month 3 weeks ago
πŸ”Ž Can US predict PsA progression from psoriasis? YES: synovio-entheseal inflammation predicts progression in 183pts prospective cohort #OP0183 #EULAR2026 @RheumNow https://t.co/7B9KU60qFd
🦴 What drives enthesophytes in PsA?

SITE-SPECIFIC:
Pelvic driven by disease activity+BMI
Calcaneal by BMI+damage

Nelly ZIADE πŸ€ Nellziade

1 month 3 weeks ago
🦴 What drives enthesophytes in PsA? SITE-SPECIFIC: Pelvic driven by disease activity+BMI Calcaneal by BMI+damage in a 1596pts cohort OP0182 #EULAR2026 @RheumNow https://t.co/4RxgjJ2V9u
❀️ Do biologics differ in MACE risk in PsA?

YES - JAKi highest risk after 2.5yrs vs TNFi/IL-17i/IL-23i in a retros

Nelly ZIADE πŸ€ Nellziade

1 month 3 weeks ago
❀️ Do biologics differ in MACE risk in PsA? YES - JAKi highest risk after 2.5yrs vs TNFi/IL-17i/IL-23i in a retrospective cohort of 22,246pts. OP0181 #EULAR2026 @RheumNow https://t.co/eQdBtMfRAY
Vasculitis Updates: Glucocorticoid use in AAV and GCA
  • 2026 EULAR Press Release
Glucocorticoids are the cornerstone of initial vasculitis treatment, used to rapidly control inflammation and protect vital organs. EULAR has recommendations that cover glucocorticoid use in ANCA associated vasculitides (AAV) and large vessel vasculitis, including giant cell arteritis (GCA).1,2 But the evidence base continues to grow about their use – especially over the long term.
Treatment for #lupus #brain #fog?!

#small #RCT of Memantine a N-methyl-D-aspartate receptor (NDAR) antagonist used in #

Janet Pope Janetbirdope

1 month 3 weeks ago
Treatment for #lupus #brain #fog?! #small #RCT of Memantine a N-methyl-D-aspartate receptor (NDAR) antagonist used in #Alzheimers SLE-more permeability in #brain #SLE -antiDNA cross reacting w NDAR #memantine N=19 v #PBO N=25 showed more improvemt #EULAR2026 @RheumNow POS701 https://t.co/qvHOy9oDS7
DESIR Cohort 10-year data (OP0102): SIJ structural lesions in #axSpA progress slowly, but prior MRI bone marrow oedema p

Antoni Chan MD (Prof) synovialjoints

1 month 3 weeks ago
DESIR Cohort 10-year data (OP0102): SIJ structural lesions in #axSpA progress slowly, but prior MRI bone marrow oedema predicts later structural damage. bDMARD exposure was associated with less erosion progression supporting early biologic treatment Abstr OP0102 @RheumNow
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