GI Abnormalities in Scleroderma A prospective Scleroderma Cohort Study found that gastrointestinal tract (GIT) involvement was common and negatively impacted quality of life, physical function, and employment, but had no effect on mortality. https://t.co/9z1ycWkCQt https://t.co/oE5RgjJ9tm

• GI Abnormalities in Scleroderma | RheumNow

Full read review of the interaction of innate immune and adaptive immune systems. https://t.co/00UUSat6yj https://t.co/HDMSfFJ7Ts

• The interaction of innate immune and adaptive immune system

Intracellular vs extracellular Calcium Pyrophosphate Crystals in 134 pts - 108 w/ intracellular & 26 w/ extracellular CPP crystals. Having Acute/chronic CPP crystal arthritis - 97% had intracellular and 62 extracellular crystals (p<0.001). Arthritis more likely to be asso w/… https://t.co/oRVNKptLfx https://t.co/06oGP4EyVJ

Upadacitinib safety across in RA, PsA, AS, atopic dermatitis >15000 Pt-Yrs exposure. Rates (per 100PYs) of Hzoster (1.6–3.6), NMSC (0–0.8) & incr CPK (4.4–7.9) higher w/ UPA vs comparators (RA, PsA); Deaths (0–0.8), SIE (0–3.9), MACE (0–0.4), VTE (<0.1–0.4), CA, malignancies… https://t.co/OoJ5OX7JyL https://t.co/vaMVFmldEB

Risk of Uveitis with Spondyloarthritis A retrospective registry study shows that uveitis may be seen in 10% with the diagnosis of axial spondyloarthritis (axSpA) but becomes more common (47%) over the next 30 years of disease. The good news is that biologic therapy can… https://t.co/96rRu77Tyl https://t.co/bGHnZ7lCIm

Long Term Antibiotics Increase Risk of RA JAMA has published a population-based retrospective cohort study showing a possible association between the long-term use of antibiotics and the risk of rheumatoid arthritis (RA). https://t.co/U7lPvTSJWO https://t.co/MrUuP6crB7

• Long Term Antibiotics Increase Risk of RA | RheumNow

GI Abnormalities in Scleroderma A prospective Scleroderma Cohort Study found that gastrointestinal tract (GIT) involvement was common and negatively impacted quality of life, physical function, and employment, but had no effect on mortality. https://t.co/6jQvKz7nmm https://t.co/1IGPe6obyS

• GI Abnormalities in Scleroderma | RheumNow

ED Delays and Hip Fracture Mortality Risk Waiting more than 4 hours in emergency care for treatment is linked to heightened risks of death and a longer hospital stay for hip fracture patients, reveals a single centre study, published online in Emergency Medicine Journal.… https://t.co/ZaIEkb7Lo5 https://t.co/P15DrXMbnj

UK Biobank study of 391 481 individuals found that a high polygenic risk score (PRS) for Hidradenitis suppurativa (HS) was assoc w/ increased risk of incident coronary artery Dz, diabetes, High LDL/TG and CRP https://t.co/ZS4w4hooKB https://t.co/DUXoFHMBqR

• Genetic Susceptibility to Hidradenitis Suppurativa and Predisposition to Cardio…

University cohort study of 673 adults w/ CLE or dermatomyositis finds that 32% take herbal supplements, esp in younger & Hispanic pts. 31% of DM experienced Dz onset or flare after supplements (vs 10% in CLE). Elderberry had highest risk of exacerbation https://t.co/BZluGYzr3t https://t.co/5zJD7AwwNK

• Prevalence and Risk of Immunostimulatory Herbal Supplement Treatment Among Auto…

Leiden Early Arthritis Clinic study (2011-17) of 431 pts found when RA is Dx in <12 wks, treatment costs were lower in Seropositive & negative RA. If Dx after 12wks, costs 316% higher in seronegative and 19% higher is autoantibody-positive RA pts https://t.co/I8QqZxIChW. https://t.co/8CRpqRiscz

• Early identification of rheumatoid arthritis: does it induce treatment-related …

A CATCH study of 2052 early RA (ERA) pts found high incidence of hypertension (26%) with the highest risk in older patients with traditional cardiovascular risk factors. Those without HTN, at enrolment, 24% developed HTN after median follow-upof 5 years. https://t.co/8MmU60MK8v https://t.co/LyxSssXKLo

• Risk factors for prevalent and incident hypertension in rheumatoid arthritis: d…

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