The fracture risk with glucocorticoids is dose dependent. Lems W #EULAR2024 @RheumNow https://t.co/TGjKu1vfXx

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#EULAR2024 POS0257 One for the future. Phase 2A RCT showed KPG-818, a Novel Cereblon Modulator (targets Aiolos & Ikaros) was well tolerated with efficacy signal (SLEDAI-2K & CLASI-50). Effect and safety profile were numerically better in the lowest dose @RheumNow https://t.co/Bjk9zBRmVo

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PsA: one composite index that does it all cDAPSA + Investigator’s Global Assessment (IGA) of PSO Cohen’s kappa 0.72 & 88% concordance with PASDAS LDA 88% sensitivity & specificity in DISCOVER-1 & 2 trial data #EULAR2024 @RheumNow POS0254 https://t.co/ZBb1M4IusC

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🚨 New 68Ga-FAPI-04-PET/CT, fibroblast activation tracer 38 PSO patients w/ arthralgia Correlation PET/CT SUVmax, TJC & tender enthesis count 68Ga-FAPI-04 uptake = higher risk developing PsA 6mo Shows signs of inflammation before MSUS! #EULAR2024 @RheumNow POS0242 https://t.co/GG6qeD4qJn

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Leflunomide for #PMR? ✅ #Leflunomide FAR more effective than #MTX in #polymyalgia #rheumatica V fast withdrawal of #prednisone #LEF ~4 to 5 months #MTX 30 mos! ⬇️flares w LEF 😮 #EULAR2024 @RheumNow @eular_org @SebaUltraTrail https://t.co/2hk0yMH6gY

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Some of these drugs dont seem to work in all of knee OA. I guess its really difficult to tease out different subtypes. Subgroup analysis from a Phase 3 intraarticular JTA-004 injection at #EULAR2024 abst#Op0305 @RheumNow https://t.co/jbkLYyl93e

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🧠POS0730 Self-reported cognitive function in older adults with #SLE in @ndb_org registry ➡️Cognitive symptoms significantly worse in older people w SLE vs other #RMDs ➡️Perceptions of cognitive function assoc with less satisfaction with health & ⬇️ #QoL @RheumNow #EULAR2024

Check point inhibitors may cause bone loss and fractures. Lems W #EULAR2024 @RheumNow https://t.co/rf1AU60Eah

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This can be coming to a clinic near you. Hotspot/ROI ratio (HRR) values from high-resolution thermographic marker in the detection of joint inflammation, compared to joint ultrasound showed excellent performance in the differentiation of joints with US inflammatory activity from… https://t.co/1unRxxgHAd https://t.co/tOPDSxzvwB

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Does TCZ switch off GCA histopathologically? GCA pts still on TCZ (median 2.4y duration) had repeat temporal artery biopsy (contralat) Despite serological remission on TCZ, a heap had active histopath findings & PET still active. Scary #EULAR2024 OP0233 Reggio Emilia @RheumNow https://t.co/TKBUP5p4R0

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RheumNow’s expanded coverage of the #EULAR2024 Annual meeting is sponsored in part by Bristol Myers Squibb and UCB. All content is chosen by RheumNow & our faculty.

Greatest chance of sustained drug-free remission (DFR) is seen in early RA pts, NEVER requiring a biologic (esp if seronegative blue line). ERA on biologics never achieve DFR (yellow). Leiden EAC clinic study of 627 ERA pts Abstr# POS0615 #EULAR2024 https://t.co/zpCG6oSE3T

Loved the talk on #VEXAS by @maferradastrong today at #EULAR2024 ! Amazing pictures to explain cellular level pathophysiology! Look for abnormal signs that arent otherwise explained to try to get to the diagnosis. @rheumnow https://t.co/YZmAqmFHpE

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