GPA Management in 2024 https://t.co/qTwI7oVMBI https://t.co/Tr0eVmcgNN

• GPA Management in 2024 | RheumNow

Practice Metrics Use by Rheumatologists in RA. 54% of Rheums do "some" measure, Most used: HAQ 36%, RAPID3 27%, CDAI 18%, Vectra 13%. More than 35% do NOT measure https://t.co/FOlyCSFF25 https://t.co/3S36tDlgcE

• Metrics Used by Rheumatologists in RA | RheumNow

TNFi mAbs, JAKi, –IL-17 are protective against Anterior Uveitis (AU) in AxSpA. Metanalysis of 44 RCTs shows AU IR: - TNF mAbs: 4.1 - etanercept 5.4 - IL-17i: 2.8 - JAKi: 1.5 - placebo: 10.8 https://t.co/qN9UL16YPO https://t.co/5WOjAq9ty6

• Incidence of Uveitis in Patients With Axial Spondylarthritis Treated With Biolo…

ILD Onset in MDA-5 Dermatomyositis MDA5 antibody-positive DM is a rare, aggressive and progressive subtype of DM. Its' severity is dependent on the development of progressive ILD, manifesting as either RPILD and CILD. https://t.co/9OPddNCLKr https://t.co/7KNCLnC3BA

• ILD Onset in MDA-5 Dermatomyositis | RheumNow

Next up! Spondyloarthritis Spectrum Tuesday, April 23, 2024 | 6:30PM ET Nonradiographic Axial Spondyloarthritis - Eric Ruderman, MD Enthesitis in Spondyloarthritis - Lihi Eder, MD Future Therapy of Axial Spondyloarthritis - Lianne Gensler, MD https://t.co/XvA0cPsC1E https://t.co/FZ3GfHpTFm

• RheumNow.com

Pregnancy in vasculitis checklist: - goals and timeline - disease activity in 12 mos - is there end organ damage? - Review Rx - h/o clots/miscarriages, APLS? - Check Ro/La - Role for ASA? - Refer to MFM Catherine Sims #RNL2024 @RheumNow

#RNL2024 @RheumNow @philseo: I now give Tociliizumab for nearly all patients with GCA GiACTA shows we weren't doing well enough with steroid monotherapy GiACTA shows dosing frequency does not make a big difference in new diagnosis, but makes a difference in relapsing disease

High risk medications for pregnancy: MTX- 40% pregnancy loss, 6-10% birth defects MMF/CYC - 40% pregnancy loss, 25% birth defects Recommend 2 forms contraception on MMF Change meds slowly to safe Rx and monitor disease activity at least 3 mos before pregnancy #RNL2024 @RheumNow

#RNL2024 @anisha_dua Throwing the kitchen sink in severe GPA CYC + RTX combo - sick population (median GFR 9, 47% on HD, 52% DAH, all received PLEX too) - 85% survival, 69% not ESKD, low rates of relapse (13% at 36 mos) But, prolonged B cell depletion, aggressive Rx

Chikungunya arthritis Metanalysis & good full-read review - 8 studies showing chronic arthritis (CCA) in minority of infected;, polyarticular, looks like RA, few seropositive, few w/ erosions on imaging. CCA may be progressive w/ irreversible damage https://t.co/8NdBCGTfxF https://t.co/SLt5COmKVf

• Bone erosions and joint damage caused by chikungunya virus: a systematic review

Hyperpigmentation from Hydroxychloroquine. From 316 HCQ pts, 26% got hyperpigmentation; delayed onset of 12 mos (6–30mos) after median cum. dose of 108 g. Seen on face (602%), Legs (36%) & hands (20%). Daily sun exposure decrease in the incidence (P=0.02) https://t.co/UX8hnwJjhs https://t.co/xU9RWCcr9C

• Hydroxychloroquine-induced pigmentation in rheumatic diseases: prevalence, clin…

RA-ILD at Higher Risk for Serious Infection and Death A prospective, multicenter study from Spain has demonstrated higher rates of mortality and serious infection in rheumatoid arthritis–associated interstitial lung disease (RA-ILD) patients. https://t.co/cjmcNi0ZqL https://t.co/wUXNWNeyOa

• RA-ILD at Higher Risk for Serious Infection and Death | RheumNow

Lupus Accelerating Breakthroughs Consortium Partners with FDA https://t.co/GW7Zy72oIZ https://t.co/AGYY8WDKcK

• Lupus Accelerating Breakthroughs Consortium Partners with FDA | RheumNow

Retrospective study of hand/feet Xrays in early/suspected #RA due to low prevalence of erosions (4.4%) seldom leading to change in Dx (2pts; 0.3%) or prognosis change (0.4%). Seronegative had less erosions; Longer Sxs not assoc w/ erosions https://t.co/YCj04ZlQJq https://t.co/fHf6EvGOyc

• Limited Diagnostic and Prognostic Value of Routine Radiographs in Newly Present…