TheDaoIndex KDAO2011
2 years 7 months ago
For pts on JAKi needing vaccines; to avoid diminishing vaccine efficacy, Dr. Winthrop noted he treats a JAKi like he would MTX in that he holds the JAKi a week after vaccinating. #RNL2024 @rheumnow
Dr. Rachel Tate uptoTate
2 years 7 months ago
Clinical pearl!
Dr. Winthrop holds JAKi for one week after vaccination.
#RNL2024 @RheumNow https://t.co/BLiKu8xX7t
Dr. Rachel Tate uptoTate
2 years 7 months ago
Dr. Strober's JAKi in dermatology takeaways!
- Consider this for AD
- Dose matters in terms of both efficacy and toxicity
- Consider combination tx
- Topical JAKi option for vitiligo, especially head and neck involvement (harder in hands and other areas)
#RNL2024 @RheumNow https://t.co/ZrPfpUF4Hz
TheDaoIndex KDAO2011
2 years 7 months ago
JAKi are being used in inflammatory skin disease other than psoriasis:
#HydradenitisSuppurativa, #alopecia, #AtopicDermatitis and #vitiligo
- Dr. B Strober #RNL2024 @rheumnow https://t.co/FzPyATPB93
Eric Dein ericdeinmd
2 years 7 months ago
Povorcitinib - JAK1 specific for Hidradenitis Suppurativa
Efficacy at 16 weeks, improvement of disease and draining tunnel count over PBO
Upadacitinib shown with benefit for HS, but not as dramatic JAK response as other derm conditions
#RNL2024 @RheumNow https://t.co/f2cxJbLi1I
Dr. Rachel Tate uptoTate
2 years 7 months ago
Face and neck vitiligo also responds to topical ruxolitinib. Dr. Strober #RNL2024 @RheumNow https://t.co/6N6A3Yq7RE
TheDaoIndex KDAO2011
2 years 7 months ago
Impressive results for alopecia totalis with baricitinib – Dr. Bruce Strober #RNL2024 @rheumnow https://t.co/OA0tpdRum2
Dr. Rachel Tate uptoTate
2 years 7 months ago
Clinical pearl! Consider topical ruxolitinib for your AD patients. Dr. Strober at #RNL2024 @RheumNow https://t.co/Sxwvn1lAXB
TheDaoIndex KDAO2011
2 years 7 months ago
Deucravacitinib takes longer to work for PsO compared to UPA, IL-17i or IL23i; it’s better than apremilast. Side effects w/TYK2i: acne, mild⬆️CK, but zoster & lipid issues aren't seen much, & no CV risk warnings; Dr. Strober doesn't follow labs w/TYK2i. #RNL2024 @rheumnow https://t.co/05jKqL4wdx
Lihi Eder lihi_eder
2 years 7 months ago
♀️ ♂️Sex Matters in Psoriatic Arthritis👉 Pleasure to discuss how to consider sex/gender in the management of PsA @RheumNow #RNL24 Dallas https://t.co/RRgzudZV0S
Eric Dein ericdeinmd
2 years 7 months ago
Clinical pearl from #RNL2024 @RheumNow
Palmoplantar psoriasis is a great time for first-line JAK inhibitor - Ben Strober, Yale dermatology
JAK for atopic dermatitis - extremely rapid responses https://t.co/hHYdGl51n2
Dr. Rachel Tate uptoTate
2 years 7 months ago
"If you are throwing a JAKi at these patients (see below) you are gonna make them better." Dr. Bruce Strober reporting on potential patients/disease states who may respond to JAKi. #RNL2024 @RheumNow https://t.co/bghPuszu5t
Eric Dein ericdeinmd
2 years 7 months ago
#RNL2024 @RheumNow
Bruce Strober on JAK in skin diseases - diverse benefits:
- PsO
- Atopic dermatitis
- Alopecia areata
- Hidradenitis suppurativa
- Vitiligo
- Lichen planus any many others https://t.co/I9XHVbFpvQ
TheDaoIndex KDAO2011
2 years 7 months ago
“JAKi can be thrown at any inflammatory skin disease and will work!” Dr. B Strober admits he uses many off-label. #RNL2024 @rheumnow https://t.co/nWzW9rMcWL
Eric Dein ericdeinmd
2 years 7 months ago
#RNL2024 @RheumNow
Winthrop on Shingrix:
Good data at 10 yrs
Diminished response in immunocompromised (chemo)
Very limited data with autoimmune patients https://t.co/cJitGOWZQt

