Md Yuzaiful Md Yusof Yuz6Yusof
3 years 3 months ago
#EULAR2023 #POS0618 This is cool! Researchers from Switzerland are developing new Quantitative Radiomic Risk Score (from HRCT) to stratify response to Anti-Fibrotic in #ILD. Data presented in pre-clinical study & paralleled molecular effects. Human study is in progress @RheumNow https://t.co/qAsWew4FEO
Janet Pope Janetbirdope
3 years 3 months ago
Is Interferon Type1 Impt in #scleroderma? #EULAR2023 OP#0114 Interferon accelerated skin fibrosis in mouse model- 61 pts 1/3 dcSSc, 2/3 lcSSc had markers of INF-1 in blood vessels &skin - more in #diffuse #SSc ?Rx opportunity w available drugs? RCT needed @RheumNow @eular_org https://t.co/vZWjSY8jKg
Janet Pope Janetbirdope
3 years 3 months ago
What would you do? A middle aged woman has pain and impaired hand function with her PIP&DIP erosive hand #osteoarthritis? Exam - jts are tender w soft tissue swelling? #NSAIDs, #denosumab, #methotrexate? 🤷‍♀️ A +RCT of #MTX in #erosive #hand #OA at #EULAR2023 @RheumNow @eular_org https://t.co/7rp3nReTPd
Aurelie Najm AurelieRheumo
3 years 3 months ago
Are we going to treat hands OA with MTX?
Moderate effect on VAS pain at 6 and 12 months in a small RCT vs. PBO in hands OA WITH MRI detected synovitis.
Thoughts
1) Is it really OA?
2) Benefit Risk balance remains debatable
@RheumNow OP0070 #EULAR23 https://t.co/WLlX48NtGT
Md Yuzaiful Md Yusof Yuz6Yusof
3 years 3 months ago
#EULAR2023 OP0083-HPR Stretch & Strength training is key! An RCT in Brazil shows: Pilates x 3/week is more effective in reducing pain, HRQoL, psychological effects & analgaesic consumption VS Aerobic walking on treadmill x 3/week for 12 weeks in women with Fibromyalgia @RheumNow https://t.co/CzIH9Xd8Ku
Bella Mehta bella_mehta
3 years 3 months ago
An interesting biomarker in #sJIA- helps differentiate it from other diseases, including infections and other inflammatory diseases! - kids with fever! serum calprotectin (MRP8/14) particle enhanced immuno-turbidimeteic assay (sCAL Turbi). 650 pts @rheumnow
#EULAR2023 abst#OP0034
Bella Mehta bella_mehta
3 years 3 months ago
#CPPD and #cervical involvement. Several clinical presentations
A-asymptomatic deposition
B-crowned dens syndrome
C-retro-odontoid pseudotumor
D-inflammatory discitis
Good teaching points in the supplements! @RheumNow #EULAR2023 Abst#AB1859 https://t.co/LJe7Gk1oZX
Bella Mehta bella_mehta
3 years 3 months ago
Remember to discuss bone density in your pts with #gout! Bone mineral density was significantly lower in pts with hyperuricemia, more so in males and elderly. Large cohort wirh 9017 pts from China! @EULAR2023 @rheumnow abst#AB1639 https://t.co/BGscJxMZno
Bella Mehta bella_mehta
3 years 3 months ago
Gut microbiome studies are implicated in all disease we study! 5 gut microbiota are suggested to have a causal relationship in #gout.
68k controls and 2k gout pts.
Can experts comment if it's just data mining or discovery? #EULAR2023 @rheumnow abst#ab1237 https://t.co/d1AkDPG8QR
Md Yuzaiful Md Yusof Yuz6Yusof
3 years 3 months ago
#EULAR2023 #OP0046 With more effective therapies in #lupus, we should aim for bare minimum/cessation of steroid. A study using French database showed:
>12% were on =>5mg Pred/d, this associated with comorbidities & increased costs
14% on high dose Pred weren’t on HCQ
@RheumNow https://t.co/x99Jt9yf1g
Md Yuzaiful Md Yusof Yuz6Yusof
3 years 3 months ago
#EULAR2023 #OP0007 What are the recent trends of autoimmune disease (AID)? A database study (22m) in UK showed:
- 1 in 10 people had AID in the last 20yrs
- socioeconomic, seasonal & regional disparities cd influence pathogenesis
- CTD (SLE,pSS,SSc) tended to co-occur @RheumNow https://t.co/3DDPR2K5NC
EULAR 2023 launched today to crowds of attendees. The opening Plenary session and presidential address by Dr. Ian McInnes was followed by a number of overview and review sessions with but a half-day of abstracts presentations, on several therapeutic areas including osteoarthritis, JIA, COVID and more. The following are a few of the presentations that caught my eye.
