Dr. John Cush RheumNow
3 years 8 months ago
Population data on incidence of #RA from Northern Savo, Finland, 46 new RA cases in 2020; incidence seropos RA was 22.3 per 100K. Incidence did not differ by gender but decreased w/ age < 55 years, p = 0.003 (change in risk factors?) https://t.co/QxMwKh7wIU
Dr. John Cush RheumNow
3 years 8 months ago
Ferritin may be more than biomarker in Stills, etc - may contribute directly to pathogenesis. Ferritin causes PMN activation & neutrophil extracellular traps (NETs). Could this be targeted therapeutically? https://t.co/42KeTbVsQb https://t.co/imLipzmf4R
Despite its well known toxicities, alcohol is known to be antiinflammatory. The effects of alcohol use in rheumatoid arthritis (RA) is less known, but a recent study suggests that alcohol consumption was dose-dependently associated with lower disease activity and higher health-related quality of life in RA patients.
Dr. John Cush RheumNow
3 years 8 months ago
ACP Guidelines on Fracture Prevention in at-risk Adults
The American College of Physicians (ACP) has updated its 2017 recommendations on pharmacologic treatment of primary osteoporosis or low bone mass to prevent fractures in adults.
https://t.co/FE6WEs1Oug https://t.co/Mvgx8sVLPh
Dr. John Cush RheumNow
3 years 8 months ago
Hosp study of 2809 admissions, found 1+adverse events (AE) in 24%. Among 978 AE, 23% (222) were preventable; 32% (316) serious. Preventable AE occurred in 1/15 admissions (serious 1/100). Drug AE were most common (39%) https://t.co/gqty53ccyH https://t.co/GxDBoEhxeM
Dr. John Cush RheumNow
3 years 8 months ago
JAK Inhibitor Promising for Polymyalgia Rheumatica
Tofacitinib appeared highly effective against PMR in a small single-arm trial, researchers said, suggesting another potential alternative to long-term corticosteroids.
https://t.co/XNhICcDU7t https://t.co/WWHNRP3aeP
Dr. John Cush RheumNow
3 years 8 months ago
"It takes alot of courage to reach out and say 'I need some help on this one'" (Carla Harris)
Put on your big-boy pants, woman-up and ask for advice, not from anyone - go to the right person/people - you know who they are! https://t.co/GUs1nCvXeU
Dr. John Cush RheumNow
3 years 8 months ago
Holes in TH17 cells release IL-1α on NLRP3 activation
Certain T cells can secrete cytokines that are normally part of the innate immune system, as researchers from the Leibniz-HKI and an international research team discovered.
https://t.co/lLHD66D3RP https://t.co/cym7SGD2WX
Dr. John Cush RheumNow
3 years 8 months ago
Free great handout on DRESS - Drug Reaction With Eosinophilia and Systemic Symptoms. May affect adults or children; usually 2 to 8 weeks after beginning a medication. ~1 in 1000 taking specific drugs get DRESS. Allopurinol is a common cause https://t.co/X8lHtGVunC https://t.co/OjCzUXWJcz
A population-based retrospective cohort study patients with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants demonstrated significant adverse pregnancy outcome, particularly the infants of women with SLE. This included maternal/infant rehospitalization, malformations and mortality.
BE COMPLETE is published, showing that bimekizumab (BMK), a selective dual inhibitor of interleukin (IL)-17F and IL-17A, results in superior improvement in both skin and joint outcomes in psoriatic arthritis (PsA) patients who have previously failed treatment with a tumour necrosis factor-α (TNFα) inhibitor.
Dr. John Cush RheumNow
3 years 8 months ago
anti-mitochondrial antibodies (AMA) in were assayed in 404 #RA patients & found to positive in 14-26%. Importantly AMA Abs were associated with erosive disease (p<0.05) and interstitial lung disease (p<0.01), independent of CCP or RF https://t.co/ZcrOYr0cWX https://t.co/KvZ3N5IiCB
Dr. John Cush RheumNow
3 years 8 months ago
10 best US jobs in2023, half are medical
1 Software developer
2 Nurse practioner
3 Medical/health serv manager
4 Physician asst
5 Information security analyst
6 Physical therapist
7 Financial manager
8 IT Manager
9 Web developer
10 Dentist https://t.co/nL5yuorzTH https://t.co/4mYspRCZX0
Dr. John Cush RheumNow
3 years 8 months ago
Cannabis Use for Pain is Common
In states with legalized medical cannabis use, 3 in 10 persons are using cannabis to manage their pain.
https://t.co/XUt1E7GcQN https://t.co/4l6vYKUOQs
Dr. John Cush RheumNow
3 years 8 months ago
Treatment Considerations in Axial Spondyloarthritis
https://t.co/GRQfk4B4QN https://t.co/xX5AYAD90c

