Dr. John Cush RheumNow
4 months 2 weeks ago
JAMA Insights on Chikungunya (affects 35 million worldwide) - mosquito-borne alphavirus seen in tropics, also travelers. Dz char by fever, disabling polyarthritis; less rash, HA, myalgia, N/V, conjunctivitis; rarely myocarditis. https://t.co/Fa3cHygc4W https://t.co/jmh2WjOcI5
Dr. John Cush RheumNow
4 months 2 weeks ago
Advanced Practice Rheum: Still's Disease and Fever
https://t.co/P3qbGYll8y https://t.co/6EAoVWimSI
An NIH lupus cohort study looked at fatigue in SLE and found associations with organ damage, obesity, but does not correlate with disease activity in systemic lupus erythematosus (SLE) patients.
Vunakizumab, a novel anti–interleukin (IL) 17A monoclonal antibody, was studied in patients with active radiographic axial spondyloarthritis [r-axSpA] and found to be effective and tolerable.
Dr. John Cush RheumNow
4 months 2 weeks ago
Registry of 587 #SLE pts. 30% were RNP+ --> more dz activity than RNP- (SLEDAI-2 8.0 vs 4.0) and more Rx use (daily GC 6.8 vs 3 mg). RNP+ more renal, skin & serologic activity & less likely to LLDAS (20% vs 32%) or REM (12% vs 23%). RNP + 18-fold more likely to be Sm+ https://t.co/3J0Uew48OS
Dr. John Cush RheumNow
4 months 2 weeks ago
PTPN22 1858C>T allele, seen in 5-15% NAmerica, often assoc. w/ autoimmune dz risk. BUT...PNAS shows Ptpn22 augments innate immunity and enhances NK activity against coronavirus infection https://t.co/1AMTuOXtoT https://t.co/9f3JdimJsG
A current review of eosinophilic granulomatosis with polyangiitis (EGPA) provides current recommendations on diagnosis and management.
Dr. John Cush RheumNow
4 months 2 weeks ago
Chronic Low Back Pain Disappointments in a Randomized Trial
Annals of Internal Medicine reports that patients with chronic low back pain (cLBP) may benefit from physical therapy (PT); but when that fails, other secondary measures (cognitive behavioral therapy (CBT) or https://t.co/17JObbXz5U
Dr. John Cush RheumNow
4 months 2 weeks ago
Vitamin D in Rheumatic Disease - Is It Good Enough?
Vitamin D in rheumatic disease — is it sufficient? Vitamin D deficiency/insufficiency is common and linked to inflammatory rheumatic diseases, raising the question of whether low vitamin D drives immune dysregulation, disease https://t.co/CLBFii2TbR
Dr. John Cush RheumNow
4 months 2 weeks ago
🚨 SAVE THE DATE
June 3–6, 2026
RheumNow is bringing you real-time coverage of #EULAR2026
👉 Breaking data
👉 Late-breakers
👉 Global expert insights
Don’t miss a moment. #Rheumatology https://t.co/hqmIdeoS4H
Dr. John Cush RheumNow
4 months 2 weeks ago
Femoral BMD & osteoporosis are independent predictors (nverse relationship) of all-cause mortality in postmenopausal women. NHANES study(2005-2018) of 2,977 postmenopausal F, OP yielded 47% incr mortality (HR 1.47) https://t.co/67Jv63X0Hx https://t.co/4vbFDydTY7
Dr. John Cush RheumNow
4 months 2 weeks ago
APR: Still's Disease
Companion slide deck for the Advanced Practice Rheum: Still's Disease and Fever video, featuring Dr. Jack Cush.
https://t.co/wsUP2zEulC https://t.co/AWSNt9Uzlg
Dr. John Cush RheumNow
4 months 2 weeks ago
Influential Rheumatoid Factors (5.8.2026)
Dr. Jack Cush reviews the news and journal articles from this past week on RheumNow.
https://t.co/BaugLQEIai https://t.co/WdWXAfB5lk
Enpatoran, an investigational oral drug that inhibits Toll-like receptors (TLR) 7 and 8, was superior to placebo in relieving lupus skin manifestations in a dose-finding phase II trial.
New research using death certificate data from 52,942 females, reveals that systemic lupus erythematosus (lupus) is a leading cause of years of potential life lost among young women in the United States, underscoring the disease’s significant and often underrecognized public health burden.
