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CKD is a gout risk factor

Impaired renal function is a known primary contributor to hyperuricemia and risk of gout. Investigators from Stanford University sought to use the Framingham Database to identify if chronic kidney disease (CKD) is an independent risk factor for gout. Among 4700+ patients and 52 years of followup, they found 371 self identified incident gout cases. After adjustments for age, sex, BMI, alcohol use, smoking, hypertension, diabetes and menopause, CKD was associated with an HR of 2.09 (95% CI 1.41 to 3.08) for gout overall, this study confirms the association between CKD and gout. [Image: "The Gout by James Gillray. Published May 14th 1799. Via copy at [1]. Licensed under Public Domain via Wikimedia Commons."]

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The author has no conflicts of interest to disclose related to this subject