Best of 2022: Acne with JAK Inhibitors

Save

JAK inhibitors have become enormously popular and while their side effect profile has been delineated and reviewed, little mention is made of acne – an adverse event that may affect up to one-quarter of patients taking JAK inhibitors (JAKi). Dermatologists often refer to this side effect as "JAKne".

New Hope for Hand Osteoarthritis

Save

The drug talarozole – which increases retinoic acid – could be a promising new treatment for hand osteoarthritis.

Best of 2022: Undifferentiated Arthritis Does Not Follow an RA Course

Save

Undifferentiated arthritis (UA) is common in medical practice and many advocate early use of DMARDs; yet a recent study shows that despite DMARD use, UA patients do not fair well with this approach.

Best of 2022: ACR/EULAR 2022 Classification Criteria for Granulomatosis with Polyangiitis

Save

The ACR/EULAR 2022 revised classification criteria for granulomatosis with polyangiitis (GPA) have been updated with performance characteristics and are validated for use in clinical research.

Metformin Reduces Osteoarthritis Risk in NIDDM Patients

Save

Osteoarthritis is a common chronic condition that usually causes joint pain and can be severe enough to require knee and hip replacements.

Best of 2022: Approach to ILD in Myositis Syndromes

Save

Mehta et al have published a full read review of managing interstitial lung disease (ILD) in patients with inflammatory myopathies, a heterogeneous group of syndromes connected by ILD and and increased morbidity and mortality risk.

Fever, FROST, & Pericarditis (12.16.2022)

Save

Dr. Jack Frost reviews the news, and journal articles from the past week on RheumNow and ends with an audience question on "Macro-CK".

COVID-19 Vaccine Responses in Rheumatic Disease Patients

Save

Nature Reviews Rheumatology features a review of three notable papers that address the impact of SARS-CoV-2 vaccination on people with inflammatory rheumatic disease. 

JAK Inhibitor Potential in Systemic Sclerosis-Associated ILD

Save

The occurrence of interstitial lung disease (ILD) in Systemic sclerosis portends serious morbid and mortal outcomes for those affected. This review examines the available clinical literature on the potential benefits and outcomes of JAK inhibitor use in SSc=ILD.

ACR New Guidelines on Integrative Approach to RA

Save

The American College of Rheumatology (ACR) released a summary of its new guideline for Exercise, Rehabilitation, Diet and Additional Integrative Interventions for Rheumatoid Arthritis.

CXCL5 Therapy in Lupus?

Save

 A new study has shown that restoring the balance of a protein in blood may be a promising treatment option for systemic lupus erythematosus.

Marginal Benefit with Diet and Exercise in Obese Knee Osteoarthritis Patients

Save

The easiest intervention for knee osteoarthritis (diet and exercise) is also the most difficult for many patients; but do these work? A new study of a weight loss and exercise program in community settings shows only marginal benefits.