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What Factors Predict RA in First-Degree Relatives?

MedPage Today

Among a cohort of first-degree relatives of patients with rheumatoid arthritis (RA), certain patient characteristics, as well as symptoms, helped predict a possible increased risk for developing the disease, U.K. researchers reported.

Booster Shots for Rheumatology Patients on Immunosuppressive Medications

ACR Press Release
ATLANTA – The CDC's Advisory Committee on Immunization Practices today recommended that rheumatology patients being actively treated with high-dose corticosteroids, alkylating agents, antimetabolites, TNF blockers, and other biologic agents that are immunosuppressive or immunomodulatory receive a third dose of the Pfizer-BioNTech or Moderna mRNA COVID-19 vaccines.

RheumNow Podcast – Booster Shots for COVID (8.13.2021)

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com.

Anakinra's Effects on COVID-19 Outcomes

Sporadic reports of anakinra use in COVID-19 infection has hinted is potential; now a metanalysis shows that the use of anakinra may reduce the mortality risk in patients admitted to hospital with moderate to severe COVID-19 pneumonia, especially highly elevated ferritin and C-reactive prote

USA Ranks 11th (Last) in Healthcare Delivery

Despite spending more (18%) of its gross national product on health care than its peers, the U.S.

COVID Vaccine Booster Effective for Transplant Recipients in Small Trial

MedPage Today

For organ transplant recipients, a third dose of Moderna's COVID-19 vaccine more than tripled the proportion with a sufficient antibody response, a randomized trial showed.

Mepolizumab Dosing in Eosinophilic Granulomatosis with Polyangiitis

A new European real world experience study shows that mepolizumab is effective at both 100 or 300mg every 4 weeks in patients with the rarely encountered eosinophilic granulomatosis with polyangiitis (EGPA; or Churg-Strauss Syndrome). 

Biologics Reduce Surgical Needs in RA

In Canada, biologic DMARDs (bDMARDs) were introduced after 2001, and since that time there have been significant reductions in hip and knee arthroplasty (THA/TKA) among patients with rheumatoid arthritis (RA), but not in patients with osteoarthritis (OA).

Rare Risk of Serious Adverse Events After COVID Vaccination

CDC/MMWR

The CDC had reported the Advisory Committee on Immunization Practices (ACIP) study of rare serious adverse events after COVID-19 vaccination and assert that the excessive morbidity and mortality from COVID-19 (and the protection afforded by vaccination) far exceeds the risk of rare safety signals

More Tea, Less Rheumatoid

A large cohort study of rheumatoid arthritis (RA) patients shows that regular tea consumption was associated with a lower risk of RA.

Early MRI Sacroiliac Improvement with JAK Inhibition

The TORTUGA trial tested filgotinib, a JAK1 inhibitor, in active ankylosing spondylitis (AS) patients and was shown to be both effective and capable of retarding sacroiliac (SI) joint erosions as early as 12 weeks.

Safety and Tolerability of Subcutaneous Methotrexate

A large, single-rheumatology center analysis of oral and subcutaneous (SC) methotrexate (MTX) use in daily clinical practice suggests that SC MTX has fewer drug discontinuations and is better tolerated compared to other DMARD therapies.

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