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AMA Proposes Ban on Television Drug Ads

The American Medical Association has called for a ban on direct-to-consumer (DTC) advertising for prescription drugs and medical devices, noting these forms of advertising drive up health care costs and often mislead the public.

SB4 - A Second Biosimilar Up For Review in Europe

A biosimilar of etanercept (Enbrel) made by the South Korean company Samsung Bioepis is under consideration by regulators in the European Union. Samsung Bioepis, a joint venture between Samsung Biologics and Biogen, is taking aim with its version of etanercept.

Alcohol and Methotrexate - What Do You Advise?

What are your rules on methotrexate and alcohol use? How about casual, social or occasional alcohol use? If one alcoholic beverage is ok, what about 2, 3 or six while taking MTX?

Tocilizumab & Abatacept Effective in Giant Cell Arteritis

Giant cell arteritis (GCA) is a medium and large vasculitis, wherein only glucocorticoids (GC) treatment has been the mainstay of therapy. As many will require prolonged treatment, the hazards of GC are well known, lead to substantial toxicity and morbidity.

Surviving Infection on DMARDs or Biologics

Sepsis is a dangerous and potentially fatal consequence of serious infections (SIE), particularly in susceptible populations such as the elderly and immunosuppressed. Published evidence points toward the potential role of TNF in development of sepsis.

Are Guidelines Worth the Cost?

A thoughtful perspective on the purpose, focus and cost of guideline efforts in rheumatology has been published in the journal Rheumatology.

Pharmacy Benefit Managers at Odds with Specialty Pharmacies

Reuters and the Wall Street Journal have reported that the largest U.S. pharmacy benefit managers (PBM) of private prescription drug benefits have cut off at least eight pharmacies that work closely with drugmakers, intensifying scrutiny of a system that helps inflate drug prices.

Hypertension Increased in Psoriasis Treated with NSAIDs, Cyclosporine or Steroids

Psoriasis and psoriatic arthritis patient have significantly higher rates of comorbidity, including hypertension (HTN). This population-based, nested case–control study analyzed an inception psoriasis cohort from Taiwan's National Health Insurance Research Database between 2000–2010.

Biology of Bone Remodeling in Psoriatic Disease

Paine and Ritchlin have reviewed the evidence that new bone formation is centered around enthesial sites and that such findings are evident in psoriatic arthritis as well as psoriasis patients without arthritis.

Is Baricitinib Really Better Than Adalimumab in RA: Trial Results Reviewed

Dr. Peter Taylor and colleagues presented their results of the 52-week BEAM trial wherein baricitinib (a JAK 1, 2 inhibitor) was compared to adalimumab in both clinical and radiographic outcomes. This was the most viewed abstract online at the ACR website.

Cryoglobulinemic Vasculitis Reviewed

Cacoub et al review the common entity cryoglobulinemic vasculitis (CryoVas) in the current issue of the American Journal of Medicine.

This small-vessel vasculitis involves the skin, joints, and potentially other organs, including the peripheral nervous system or the kidneys.

Are We Using Methotrexate Appropriately?

Methotrexate is a mainstay drug in the treatment of rheumatoid arthritis (RA).  Yet, we may not be using it long enough or optimizing its use.  

ACP Releases Paper on Impact of 'Concierge' on Patient Care

The American College of Physicians released a position paper exploring factors driving the growth of “concierge” and other “direct patient contracting practices” (DPCPs) and the “limited” evidence on their impact on patient care.

Concern Still Lingers for Silicone Breast Implants

What do you tell your patients who are considering augmentation mammoplasty? Or who question the safety of prior implants?

Anifrolumab Improves Lupus Outcomes

Furie and coworkers presented the results of a 52-week phase II trial of anifrolumab (ANIFR), a type I interfernon (IFN) receptor antagonist in patients with lupus (SLE).

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