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Continuously elevated serum matrix metalloproteinase-3 (MMP-3) for 3-6 months predicted 1-year radiographic progression in rheumatoid arthritis (RA), according to a small prospective cohort study in Arthritis Researc
Prescription drugs may cost up to 10 times more in the United States than they do in other countries, according to a 2013 Comparative Price Report was released last month by the International Federation of Health Plans (IFHP).
A number of studies have shown that the treat-to-target approach is effective in achieving clinical remission - the ultimate therapeutic goal in patients with early RA.
Lesinurad is a novel URAT-1 inhibitor being developed as a urate-lowering therapy for gout by Astra-Zeneca.
A recent presentation at the European Academy of Dermatology and Venereology (EADV) meeting in Copenhagen showed the long-term outcomes of weight loss in psoriasis.
Zhang and colleagues from Boston analyzed patients with physician diagnosed sleep apnea from The Health Improvement Network in the UK and compared these with 5 controls (age, sex, BMI matched). They studied 9,865 patients with sleep apnea and 43,598 controls.
A retrospective analysis examined whether it's better to initiate urate-lowering therapy (ULT) during or after an attack of acute gout.
UK investigators have shown that rheumatoid arthritis patients with bronchiectasis (BRRA) have a five-fold increased mortality compared to RA without bronchiectasis. It is unclear if serologic differences, activity measures and biomarkers may be different in this cohort.
Using data from the Nurses' Health Study (NHS), Sparks and colleagues analyzed 119,209 women beginning in 1976. The identified 964 incident RA cases and 28,808 deaths during 36 years of prospective follow-up.
In the USA, toxoplasmosis is the second leading cause of foodborne illness–related death and hospitalization, with >300 deaths and 4000 hospitalizations each year [2]; 4800 people develop visual loss yearly secondary to the parasite.
Healio.com reports that pregnant women with APL antibodies and who took Plaquenil (HCQ or hydroxychloroquine) had better pregnancy outcomes than those who did not.
Patients in the U.S. with myositis who are positive for the anti-MDA5 autoantibody are at high risk for developing interstitial lung disease (ILD), a retrospective study found.
The FDA has denied Pfizer's application seeking an indication for Xeljanz in patients with moderate to severe chronic plaque psoriasis.
The CDC has reported in the NEJM that dietary supplements may be associated with higher than expected rates of adverse events requiring medical evaluation in the emergency department (ED).
The Journal of Clinical Investigation reports a potential decline in the number of medical researchers in the future.
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