Biosimilars are copies of the biologic medicines used to treat inflammatory and immunologic conditions such as rheumatoid arthritis, multiple sclerosis and cancer- potentially at lower costs.
A retrospective review of 1285 US male veterans showed the prevalence of inflammatory eye disease to be 2%. Uveitis was most common (most being anterior uveitis), followed by keratitis, scleritis, episcleritis, and acute ischemic optic neuropathy.
1998 marked the introduction of citrulline as a unique target in the pathogenesis of rheumatoid arthritis. The hallmark article by Schellekens et al in the Journal of Clinical Investigation has since been cited over 500 times. Dr.
The National Institute for Heath and Care Excellence has turned down Otezla for coverage under the U.K. healthcare system for psoriatic arthritis.
An incident cohort study from Denmark showed that 84 SLE pregnancies resulted in 62 live births. Lupus disease activity strongly influenced maternal complications seen in half and fetal complications were observed in one-third of cases.
A randomized controlled trial of compared the outcomes of surgical decompression or physical therapy in 169 lumbar spinal stenosis patients. After two years, intention-to-treat analyses revealed no difference between groups.
Estimates on the prevalence of psoriatic arthritis among psoriasis patients has varied widely, ranging from 5-40%. A systematic review of the literature shows that prevalence of undiagnosed PsA was 15.5% when all studies were considered and 10.1% when only epidemiological studies were consi
Cardiovascular (CV) risk and adverse cardiac outcomes are common in rheumatoid arthritis (RA). It has been presumed that chronic systemic inflammation has a deleterious effect on the myocardium and vasculature, thereby leading to higher rates of MI, CHF and CV death.
Using ultrasound guided intraarticular injection of the hip, 98 OA of the hip patients were randomized to receive IA ketorolac or triamcinolone. At, 1, 3, and 6 mos pain scale and Harris hip scores were improved equally in both groups with no statistical differences.
A large Swedish cohort study of hypertensive men and women presented at the 25th Scientific Meeting of the European Society of Hypertension, identitied a protective effect on osteoporotic fractures among current users of thiazide diuretic drugs independent of blood pressure level. This retr
Idiopathic pulmonary fibrosis carries a high mortality rate and can be a management challenge. Moreover, exacerbations of IPF may be fatal. A multicenter uncontrolled study examined the utility of targeting autoantibody production with revealed surprising results.
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