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Guselkumab gets FDA Nod for X-ray Protection

The U.S. Food and Drug Administration (FDA) has approved Johnson & Johnson's supplemental Biologics License (sBLA) to include evidence in the guselkumab (Tremfya) label for the inhibition of progression of structural joint damage in adults with active psoriatic arthritis (PsA). 

Count Your Telangiectasias (5.29.2026)

Dr. Jack Cush reviews the news, journal articles and missed quiz questions.

Increased Polypharmacy in SLE Patients

A cross-sectional study of US adults with systemic lupus erythematosus (SLE) shows significantly increased prevalence of polypharmacy, related to age, disease outcomes and often, non-SLE common medications.

Integrating D2T into T2T Practices in RA

EurekAlert!

Researchers at Semmelweis University analyzed how depression, smoking, obesity, sleep disorders, and other health problems are linked to difficult-to-treat rheumatoid arthritis (D2T-RA) and how this can inform treat-to-target (T2T) and individualized therapy.

LRA Awards for Immune Resetting Therapies in Lupus

Lupus Research Alliance

Lupus Research Alliance (LRA), the world’s largest private funder of lupus research, in collaboration with Genentech, a member of the Roche Group, announced the inaugural recipients of t

WSJ: Nurse Practitioner Is Now the Hottest Job in Healthcare

The Wall St. Journal has published a perspective on nurse practitioners (NP) and their very promising careers.

RepurpSS-II: Hydroxychloroquine plus Leflunomide in Sjögren's

A small, pilot, phase 2b trial has shown that the combination of leflunomide and hydroxychloroquine (LEF+HCQ) was effective and safe in treating patients with active Sjögren's disease.

Trends and Innovations in Lupus Nephritis Clinical Trials

Xu et al. from Shanghai University have written an analysis of global lupus nephritis (LN) clinical trials and call for innovation.

Quiz Talk (5.22.2026)

Dr. Jack Cush talks of birthdays, Quizzes and journal articles this week on the podcast.

BE BOLD Week 16 data - Bimekizumab vs. Risankizumab in PsA

UCB has released the Week 16 results from BE BOLD trial that will be presented at EULAR 2026 in London on Saturday, June 6.

A Role for Plasmacytoid Dendritic Cells in Lupus

Plasmacytoid dendritic cells (pDCs) have been strongly implicated in the pathogenesis of lupus, as their primary product, type I interferon, drive systemic lupus erythematosus and cutaneous lupus erythematosus. A recent comprehensive review synthesizes the available data on pDCs, and, importantly, what we still don't know.

Early GI Involvement Predictive of Scleroderma Outcomes

Rheumatology has published a cohort study showing that earlyGI symptoms and overall symptom burden predict both GI progression and mortality in Systemic Sclerosis (SSc).

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