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Without DMARDS, Shoulder Arthroplasty Increasing in Rheumatoid Arthritis The need for total shoulder arthroplasty (TSA

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Dr. John Cush
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Without DMARDS, Shoulder Arthroplasty Increasing in Rheumatoid Arthritis The need for total shoulder arthroplasty (TSA) in rheumatoid arthritis (RA) patients appears to depend on the use of DMARDs, according to Seminars in Arthroplasty. https://t.co/iGAQaa7Ppc https://t.co/AbteC427wI

Does Methotrexate Increase Skin Cancer Risk? A report from the British Journal of Cancer has also shown an increased ri

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Dr. John Cush
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Does Methotrexate Increase Skin Cancer Risk? A report from the British Journal of Cancer has also shown an increased risk of basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC) with MTX use; and more so with higher doses. https://t.co/tNNpFC6LiN https://t.co/x8Fuus2r8O

Deucravacitinib - Effective in Systemic Lupus Erythematosus A Phase II, multicenter study has demonstrated the efficacy

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Dr. John Cush
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Deucravacitinib - Effective in Systemic Lupus Erythematosus A Phase II, multicenter study has demonstrated the efficacy and safety of deucravacitinib, an oral, selective, allosteric inhibitor of TYK2, in adults with active SLE. https://t.co/0g2VM6TJt6 https://t.co/f6wylPc5ep

Recent Cochrane review of Vit D, Calcium and OP shows no evidence to support the isolated or combined use of calcium &am

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Dr. John Cush
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Recent Cochrane review of Vit D, Calcium and OP shows no evidence to support the isolated or combined use of calcium & vit D in premenopausal women to improve BMD (hip or spine) or results in the prevention of fractures (vertebral and non‐vertebral). https://t.co/ZbXuPAJcGv https://t.co/pai4gmMKoI

Retrospective cohort study of Taiwan Health Insurance Database looked at risk of #SLE in pts w/ Hashimoto’s thyroidit

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Dr. John Cush
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Retrospective cohort study of Taiwan Health Insurance Database looked at risk of #SLE in pts w/ Hashimoto’s thyroiditis (HT). Compared 15K HTvs 31K controls. SLE was incr in HT pts (IRR 3.58; p < 0.01). Several sensitivity analyses aHR 4.35 to 5.11 https://t.co/QaWEN4Chw9 https://t.co/bD8zrCJEXY

NLRP12 is a negative regulator of innate immune activation and type I interferon production. SLE PBMCs have low levels N

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Dr. John Cush
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NLRP12 is a negative regulator of innate immune activation and type I interferon production. SLE PBMCs have low levels NLRP12 (inverse correl w/ IFNa & Hi Dz activity. NLRP12 knockouts or deficiency Incr autoAbs, inflammation & renal damage https://t.co/VICAqKmK9r https://t.co/MxqcNzh6BQ

New 5 Peptide Autoantibody Panel Complements RA Diagnosis Antibodies to peptides not currently used for rheumatoid art

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Dr. John Cush
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New 5 Peptide Autoantibody Panel Complements RA Diagnosis Antibodies to peptides not currently used for rheumatoid arthritis (RA) diagnosis helped identify patients with untreated early disease that conventional biomarkers missed, researchers said. https://t.co/lOZvXBp7c1 https://t.co/6JVpeOyGYu
Older Lupus Patients Need Follow-Up After Hospital Discharge

Medicare beneficiaries 65 and older with lupus faced dramatically higher mortality when they received no follow-up care during the month after a hospital stay, researchers found.

Death rates within 30 days of discharge were 65% higher in the absence of 30-day follow-up compared with older lupus patients who did receive it, according to Christie M. Bartels, MD, MS, of the University of Wisconsin in Madison, and colleagues.

Systemic Sclerosis cohort study of 506 SSc pts with saw 5.3 with Degos-like lesions (89% in fingers). Degos lesions more

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Dr. John Cush
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Systemic Sclerosis cohort study of 506 SSc pts with saw 5.3 with Degos-like lesions (89% in fingers). Degos lesions more assoc w/ diffuseSSc & acro-osteolysis, digital ulcers, and calcinosis (but not renal crisis, ILD, or pulmonary HTN https://t.co/eCumzZvEmO https://t.co/B41NLt4RYF
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