Leflunomide versus azathioprine in lupus nephritis? Study of 215 bx proven LN given either LEF or AZA - Renal flares wer

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Leflunomide versus azathioprine in lupus nephritis? Study of 215 bx proven LN given either LEF or AZA - Renal flares were equal (15.7% v 17.8%), as was time to flare (16 mo vs AZA 14 mo); 24-hr proteinuria, creatinine, C3 and C4 improved similarly. https://t.co/fbzhuFT3lh

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https://bit.ly/3PDEsaQ

From the Hopkins Lupus cohort - Just one month of Prednisone 40 mg/d yields a FOUR fold increase in avascular necrosis r

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RheumNow

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From the Hopkins Lupus cohort - Just one month of Prednisone 40 mg/d yields a FOUR fold increase in avascular necrosis risk #UTSWSLE2022 https://t.co/Kae2PMVgl7 https://t.co/XuhbkBwlCw

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https://bit.ly/3hzhBRo

MTX side effects more prominent in PsA than RA pts. Study of 240 PsA &amp; 86108 RA pts starting either MTX or TNFi.

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RheumNow

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MTX side effects more prominent in PsA than RA pts. Study of 240 PsA & 86108 RA pts starting either MTX or TNFi. TNFi AE same betw PsA & RA, but MTX adverse greater in PsA (44.8% vs. 29.4%), especially N/V, abdominal pain, depression, tinnitus https://t.co/qpGYDguYBK https://t.co/KUNQrSBNO2

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https://bit.ly/3v4PoVI

Cancer Risk with Scleroderma Spanish Scleroderma Registry examined a large cohort of systemic sclerosis (SSc) patients

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RheumNow

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Cancer Risk with Scleroderma Spanish Scleroderma Registry examined a large cohort of systemic sclerosis (SSc) patients showing an increased cancer risk, especially breast, lung, hematologic and colorectal cancer. https://t.co/S3EHajMF9q #BestOf2022 https://t.co/kV772Jef4V

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https://bit.ly/3WwbOus

#BestOf2022 Metanalysis of 7 studies shows that oral anticoagulants need not be discontinued for joint injections or a

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RheumNow

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#BestOf2022 Metanalysis of 7 studies shows that oral anticoagulants need not be discontinued for joint injections or aspiration. Only pts w/ hemorrhage after 5427 procedures, over 32-yrs. INR values of 3 bleeding cases was 1.9, 2.3, and 3.4. https://t.co/8e1zIhDTJt https://t.co/L4vIkWf2OL

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https://bit.ly/3V8L9D1

20 December 2022

Best of 2022: ACR/EULAR 2022 Classification Criteria for Granulomatosis with Polyangiitis

The ACR/EULAR 2022 revised classification criteria for granulomatosis with polyangiitis (GPA) have been updated with performance characteristics and are validated for use in clinical research.

20 December 2022

Best of 2022: Methotrexate in PsA

Until the publication of the SEAM trial, evidence in the medical literature for the efficacy of the most commonly used drug for psoriatic arthritis worldwide, methotrexate, has been lukewarm at best. Yet we all employ it commonly, either as monotherapy or in combination with biologic or targeted synthetic DMARD treatment. It is inexpensive and widely available, and only modestly toxic.

#BestOf2022 Co-administration of MTX with Folic Acid on the same day did not reduce efficacy compared to FA applicatio

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RheumNow

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#BestOf2022 Co-administration of MTX with Folic Acid on the same day did not reduce efficacy compared to FA application one day after MTX. (based on AIA was induced in female Lewis rats) https://t.co/uh78ZdsqgP https://t.co/j32q68DU0X

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https://bit.ly/3VaD40o

COVID-19 Vaccine Responses in Rheumatic Disease Patients Nature Reviews Rheumatology features a review of three notable

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RheumNow

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COVID-19 Vaccine Responses in Rheumatic Disease Patients Nature Reviews Rheumatology features a review of three notable papers that address the impact of SARS-CoV-2 vaccination on people with inflammatory rheumatic disease. https://t.co/R9UM3amPRR. https://t.co/WmHyVKdsxw

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https://bit.ly/3BKdCYP

JAK Inhibitor Potential in Systemic Sclerosis-Associated ILD The occurrence of interstitial lung disease (ILD) in Syste

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RheumNow

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JAK Inhibitor Potential in Systemic Sclerosis-Associated ILD The occurrence of interstitial lung disease (ILD) in Systemic sclerosis portends serious morbid and mortal outcomes for those affected. https://t.co/I1TCG3AtaW https://t.co/T7r2VKBPhG

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https://bit.ly/3BNd4l1

Topics

Leflunomide versus azathioprine in lupus nephritis? Study of 215 bx proven LN given either LEF or AZA - Renal flares wer

From the Hopkins Lupus cohort - Just one month of Prednisone 40 mg/d yields a FOUR fold increase in avascular necrosis r

MTX side effects more prominent in PsA than RA pts. Study of 240 PsA &amp; 86108 RA pts starting either MTX or TNFi.

Cancer Risk with Scleroderma Spanish Scleroderma Registry examined a large cohort of systemic sclerosis (SSc) patients

#BestOf2022 Metanalysis of 7 studies shows that oral anticoagulants need not be discontinued for joint injections or a

#BestOf2022 Co-administration of MTX with Folic Acid on the same day did not reduce efficacy compared to FA applicatio

COVID-19 Vaccine Responses in Rheumatic Disease Patients Nature Reviews Rheumatology features a review of three notable

JAK Inhibitor Potential in Systemic Sclerosis-Associated ILD The occurrence of interstitial lung disease (ILD) in Syste

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Leflunomide versus azathioprine in lupus nephritis? Study of 215 bx proven LN given either LEF or AZA - Renal flares wer

From the Hopkins Lupus cohort - Just one month of Prednisone 40 mg/d yields a FOUR fold increase in avascular necrosis r

MTX side effects more prominent in PsA than RA pts. Study of 240 PsA &amp;amp; 86108 RA pts starting either MTX or TNFi.

Cancer Risk with Scleroderma Spanish Scleroderma Registry examined a large cohort of systemic sclerosis (SSc) patients

#BestOf2022 Metanalysis of 7 studies shows that oral anticoagulants need not be discontinued for joint injections or a

#BestOf2022 Co-administration of MTX with Folic Acid on the same day did not reduce efficacy compared to FA applicatio

COVID-19 Vaccine Responses in Rheumatic Disease Patients Nature Reviews Rheumatology features a review of three notable

JAK Inhibitor Potential in Systemic Sclerosis-Associated ILD The occurrence of interstitial lung disease (ILD) in Syste

MTX side effects more prominent in PsA than RA pts. Study of 240 PsA & 86108 RA pts starting either MTX or TNFi.