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Fat and bone are never alone: osteoporotic fracture in RA Dr. David Liew discusses Abstract 889 at #ACR22. Abstract 88

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Dr. John Cush
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Fat and bone are never alone: osteoporotic fracture in RA Dr. David Liew discusses Abstract 889 at #ACR22. Abstract 889: Serum Adipokines Predict Incident Osteoporotic Fracture in Patients with Rheumatoid Arthritis https://t.co/4IrdQBq1z2 https://t.co/2HySVG1SGY

Topic Podcasts #ACR22 - SpA Part3 -Opioids and Health Care Utilization in PsA and AS -Reproductive health in a post-Ro

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Dr. John Cush
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Topic Podcasts #ACR22 - SpA Part3 -Opioids and Health Care Utilization in PsA and AS -Reproductive health in a post-Roe world -SpA: Novel Therapies, Diagnostic Dilemmas and Depression -Tapering TNFi in nonradiographic AxSpA and more https://t.co/hXPlQaxPWs https://t.co/2SRYS6EOr7
Low Dose IL-2 Therapy in Sjögren’s

There is a large, unmet need in treating Sjögren’s syndrome, yet a new randomized clinical trial has shown that low-dose interleukin 2 (LD-IL-2) was effective effective and well tolerated in patients with primary Sjögren’s syndrome (pSS), with evidence of restored immune balance.

Tyk2 Inhibition Effective in SLE Deucravacitinib, an oral, selective TYK2 inhibitor, has demonstrated efficacy in a ph

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Dr. John Cush
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Tyk2 Inhibition Effective in SLE Deucravacitinib, an oral, selective TYK2 inhibitor, has demonstrated efficacy in a phase II trial active systemic lupus erythematosus (SLE) patients. https://t.co/cpbDnkfUIS https://t.co/xct8dACBAY

RCT data on BTK inhibitor evobrutinib shows it to be well tolerated. Ph 2 RCT data on 1083 pts (RA, MS, SLE) Rx w/ evob

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Dr. John Cush
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RCT data on BTK inhibitor evobrutinib shows it to be well tolerated. Ph 2 RCT data on 1083 pts (RA, MS, SLE) Rx w/ evobrutinib(861) or placebo(271) for ~ 6 mos. No diff in TEAEs or EAIR , 2 deaths (SLE), SIE 2-3/100PY https://t.co/4HOTKuCAUi https://t.co/u7KSD6RN4q

Study of 294 SLE pts on HCQ (2005-2021): 37 (13%) developed CHF w/ low EF (HFrEF), arrhythmia or cardiac death. After a

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Dr. John Cush
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Study of 294 SLE pts on HCQ (2005-2021): 37 (13%) developed CHF w/ low EF (HFrEF), arrhythmia or cardiac death. After adjustments, wt-based dosing of HCQ not assoc w/ cardiac events(sHR 0.62; 0.41,0.92) & may decrease risk in non-smokers https://t.co/ufYcnuMI2r https://t.co/cOPIUpwpHf

JAMA - Update/Review of Hemochromatosis Dx and Rx. - 5 gene defects in hepcidin. 95% HFE & the C282Y variant - 90%ar

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Dr. John Cush
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JAMA - Update/Review of Hemochromatosis Dx and Rx. - 5 gene defects in hepcidin. 95% HFE & the C282Y variant - 90%are asymptomatic - Suspicion w/ arthralgias, LFTs, hepatomegaly, cardiomyopathy, 1st degr relative - Untreated, 9% risk of cirrhosis https://t.co/nuq8Ioralk https://t.co/djwlVsIk3b

#ACR22 - SpA Part2 -Comorbidities in Ankylosing Spondylitis -Early Diagnosis of AxSpA -Fertility issues in SpA -Gen

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Dr. John Cush
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#ACR22 - SpA Part2 -Comorbidities in Ankylosing Spondylitis -Early Diagnosis of AxSpA -Fertility issues in SpA -Gender in AxSpa -Inadequate Dosing of HCQ Leads to Hospitalizations in SLE -JAK inhibitors in RD -Opioid use in PsA and SpA https://t.co/1xJzSmekR2 https://t.co/kxpLGi8Ky4
ACR22 Takeaways: Pre-RA, Lupus, PsA and AS
ACR22 Convergence left us bountiful with information from all over the world. Here are a few of my personal highlights and key takeaways. 
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