RT @AurelieRheumo: Systemic Inflammation Index (neutrophils*platelet count/lymphocyte count) predicts survival in RA in

Tweet Author

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Systemic Inflammation Index (neutrophils*platelet count/lymphocyte count) predicts survival in RA in 1000+ pts All cause mortality OR 2.64 CV-mortality OR 3.03 Another proof (if needed) of asso inflammation & mortality in RA https://t.co/A77iPTTfTM Abs#1650 #ACR22 @RheumNow https://t.co/8aHYAZEg6v

Links

Systemic Immune Inflammation Index Predict All-Cause and Cardiovascular Mortali… http://bit.ly/3USR7bh

RT @RHEUMarampa: Dr. Ogdie proposes a whole-patient care approach to the treat-to-target strategy in SpA with QoL as the

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RHEUMarampa

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Dr. Ogdie proposes a whole-patient care approach to the treat-to-target strategy in SpA with QoL as the most important target. #ACR22 @Rheumnow @rheumarhyme @trishiemd https://t.co/GjLt2Nym3I

RT @RichardPAConway: Nestor et al. HCQ <5mg/kg day assoc increased hospitalisation for SLE flare. aOR 4.41 (95% CI 1.

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RichardPAConway

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Nestor et al. HCQ <5mg/kg day assoc increased hospitalisation for SLE flare. aOR 4.41 (95% CI 1.50-12.98) @RheumNow #ACR22 Abstr#1654 https://t.co/I4bTu2DWaR https://t.co/jpOwHUTenk

Links

Hydroxychloroquine Dosing Less Than 5 Mg/kg/day Leads to Increased Hospitalizat… https://acrabstracts.org/abstract/hydroxychloroquine-dosing-less-than-5-mg-kg-d…

RT @RichardPAConway: Tuttle et al. Phase 2 RCT of Peresolimab (PD-1 stimulator) in DMARD-IR RA. Evidence of efficacy. No

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RichardPAConway

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Tuttle et al. Phase 2 RCT of Peresolimab (PD-1 stimulator) in DMARD-IR RA. Evidence of efficacy. No new safety signals @RheumNow #ACR22 Abstr#L03 https://t.co/vhrmtGTjw1 https://t.co/k1LLk95bv1

Links

A Phase 2 Trial of Peresolimab for Adults with Rheumatoid Arthritis - ACR Meeti… https://acrabstracts.org/abstract/a-phase-2-trial-of-peresolimab-for-adults-wit…

RT @KDAO2011: #ACR22 #GIO #Osteoporosis Guidelines Case: "Young skeletons recover bone loss rapidly after GC are discon

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KDAO2011

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#ACR22 #GIO #Osteoporosis Guidelines Case: "Young skeletons recover bone loss rapidly after GC are discontinued." In these pts, despite daily pred 10 mg/day, they just needs Ca/Vit D, lifestyle mod, and monitoring. @rheumnow https://t.co/a5DVZoB3l8

RT @AurelieRheumo: A new murine model to study Pso and PsA! Immunodeficient mice NSG-SGM3 ð injected w/ serum &

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AurelieRheumo

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A new murine model to study Pso and PsA! Immunodeficient mice NSG-SGM3 🐁 injected w/ serum & PBMCs from Pso and/or PsA pts = pro & arthritis (same phenotype than pts) Mice skin & synovia >effector memory CD8 T cell & < naïve https://t.co/cxSvEZC9Ly Abs#L04 #ACR22 @Rheumnow https://t.co/hfbtSsP3f8

Links

Psoriatic Arthritis Disease Subtypes Mediated by CD8 T Cells Are Phenocopied in… http://bit.ly/3TzARem

RT @KDAO2011: #ACR22 #GIOP Guidelines Case: In pt < 40 yo who had renal transplant on 7.5 mg/day or higher with low

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KDAO2011

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#ACR22 #GIOP Guidelines Case: In pt < 40 yo who had renal transplant on 7.5 mg/day or higher with low Z score, consult mineral/metabolism expert but you can consider Rx. @rheumnow https://t.co/RJuRi7EPX1

RT @RHEUMarampa: Are we giving enough HCQ?ð¤ Findings from the study of Dr J Nestor show that â¬ï¸dose HCQ (</=

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RHEUMarampa

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Are we giving enough HCQ?🤔 Findings from the study of Dr J Nestor show that ⬇️dose HCQ (</= 5mkd or <400mg/day) is associated w/ ⬆️hospitalizations for #lupus (adj. OR 4.41; 3.48) #ACR22 @RheumNow ABST#1654 @rheumarhyme #ACRBest https://t.co/XCoZgbdOim

RT @KDAO2011: Is he the only one? Dr. Stone shared that he kept his notes from internship and residency! I kept an old

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KDAO2011

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Is he the only one? Dr. Stone shared that he kept his notes from internship and residency! I kept an old tshirt from college, but this is a new level. #ACR22 @rheumnow https://t.co/Wj9c2Uizxt

14 November 2022

Dual inhibition of IL17A and IL17F in AxSpA

A new target for treatment in AxSpA is the dual inhibition of IL17A and IL17F (IL17A/F). IL17A is a key driver of the inflammation in the AxSpA and Psoriatic Arthritis (PsA). IL17A and its structurally related IL17F share biologic functional properties. Inhibition of both cytokines (IL17A/F) should result in a greater clinical benefit in AxSpA and PsA than IL17A inhibition alone.

Topics

RT @AurelieRheumo: Systemic Inflammation Index (neutrophils*platelet count/lymphocyte count) predicts survival in RA in

RT @RHEUMarampa: Dr. Ogdie proposes a whole-patient care approach to the treat-to-target strategy in SpA with QoL as the

RT @RichardPAConway: Nestor et al. HCQ <5mg/kg day assoc increased hospitalisation for SLE flare. aOR 4.41 (95% CI 1.

RT @RichardPAConway: Tuttle et al. Phase 2 RCT of Peresolimab (PD-1 stimulator) in DMARD-IR RA. Evidence of efficacy. No

RT @KDAO2011: #ACR22 #GIO #Osteoporosis Guidelines Case: "Young skeletons recover bone loss rapidly after GC are discon

RT @AurelieRheumo: A new murine model to study Pso and PsA! Immunodeficient mice NSG-SGM3 ð injected w/ serum &

RT @KDAO2011: #ACR22 #GIOP Guidelines Case: In pt < 40 yo who had renal transplant on 7.5 mg/day or higher with low

RT @RHEUMarampa: Are we giving enough HCQ?ð¤ Findings from the study of Dr J Nestor show that â¬ï¸dose HCQ (</=

RT @KDAO2011: Is he the only one? Dr. Stone shared that he kept his notes from internship and residency! I kept an old

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RT @AurelieRheumo: Systemic Inflammation Index (neutrophils*platelet count/lymphocyte count) predicts survival in RA in

RT @RHEUMarampa: Dr. Ogdie proposes a whole-patient care approach to the treat-to-target strategy in SpA with QoL as the

RT @RichardPAConway: Nestor et al. HCQ &lt;5mg/kg day assoc increased hospitalisation for SLE flare. aOR 4.41 (95% CI 1.

RT @RichardPAConway: Tuttle et al. Phase 2 RCT of Peresolimab (PD-1 stimulator) in DMARD-IR RA. Evidence of efficacy. No

RT @KDAO2011: #ACR22 #GIO #Osteoporosis Guidelines Case: "Young skeletons recover bone loss rapidly after GC are discon

RT @AurelieRheumo: A new murine model to study Pso and PsA! Immunodeficient mice NSG-SGM3 ð injected w/ serum &amp;

RT @KDAO2011: #ACR22 #GIOP Guidelines Case: In pt &lt; 40 yo who had renal transplant on 7.5 mg/day or higher with low

RT @RHEUMarampa: Are we giving enough HCQ?ð¤ Findings from the study of Dr J Nestor show that â¬ï¸dose HCQ (&lt;/=

RT @KDAO2011: Is he the only one? Dr. Stone shared that he kept his notes from internship and residency! I kept an old

RT @RichardPAConway: Nestor et al. HCQ <5mg/kg day assoc increased hospitalisation for SLE flare. aOR 4.41 (95% CI 1.

RT @AurelieRheumo: A new murine model to study Pso and PsA! Immunodeficient mice NSG-SGM3 ð injected w/ serum &

RT @KDAO2011: #ACR22 #GIOP Guidelines Case: In pt < 40 yo who had renal transplant on 7.5 mg/day or higher with low

RT @RHEUMarampa: Are we giving enough HCQ?ð¤ Findings from the study of Dr J Nestor show that â¬ï¸dose HCQ (</=