RT @RichardPAConway: Deane et al STOP RA trial. DBRCT HCQ vs PBO pre-RA. Treat 1 year, stop, 2 year follow up. Does not

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RichardPAConway
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Richard Conway
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Deane et al STOP RA trial. DBRCT HCQ vs PBO pre-RA. Treat 1 year, stop, 2 year follow up. Does not prevent RA development. Literally no effect at all, even during treatment phase. @RheumNow #ACR22 Abstr#1604 https://t.co/7jHv7cs5DT https://t.co/GNblKs90RU
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Hydroxychloroquine Does Not Prevent the Future Development of Rheumatoid Arthri… https://acrabstracts.org/abstract/hydroxychloroquine-does-not-prevent-the-futur…

RT @RichardPAConway: Hoffmann-Vold. ILD in pSS. Frequently progressive - 21% FVC, 32% DLCO, 45% HRCT progression over 1

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RichardPAConway
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Richard Conway
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Hoffmann-Vold. ILD in pSS. Frequently progressive - 21% FVC, 32% DLCO, 45% HRCT progression over 1 year. @RheumNow #ACR22 Abstr#2049 https://t.co/um3845jOFC https://t.co/64BEB2VyG0
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ILD Associated with Primary Sjögren’s Syndrome Is Frequently Progressive - ACR … https://acrabstracts.org/abstract/ild-associated-with-primary-sjogrens-syndrome…

Sarilumab in Polymyalgia Rheumatica: Results from SAPHYR Trial

RT @Janetbirdope: New SLE Rx. Deucravitinib a TYK2i phase 2 RCT showed SRI4 endpoint. Subset of 3 mg bid was best vs 6 m

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Janet Pope
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New SLE Rx. Deucravitinib a TYK2i phase 2 RCT showed SRI4 endpoint. Subset of 3 mg bid was best vs 6 mg bid and 12 mg OD. Skin via CLASI-50 & other endpoints also positive. Awaiting phase III. Abst1117 #ACR22 @RheumNow https://t.co/fZI3AV5pML

RT @RichardPAConway: Hidekawa et al. HCQ use assoc reduced severe infection in LUNA SLE registry, HR 0.26. ?due to bette

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Richard Conway
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Hidekawa et al. HCQ use assoc reduced severe infection in LUNA SLE registry, HR 0.26. ?due to better disease control rather than anti-infectious role, but HR 0.32 in multivariable model including SLEDAI. @RheumNow #ACR22 Abstr#2059 https://t.co/EgTJOAymoF https://t.co/gmchk9ZS5L
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Association of Hydroxychloroquine with the Incidence of Infectious Disease in S… https://acrabstracts.org/abstract/association-of-hydroxychloroquine-with-the-in…

RT @Janetbirdope: Is #Tofacitinib an option in #PMR poly myalgia rheumatica? RCT of Tofa 5 mg bid vs prednisone 15 mg/d

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Janet Pope
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Is #Tofacitinib an option in #PMR poly myalgia rheumatica? RCT of Tofa 5 mg bid vs prednisone 15 mg/d and tapering. Equal results. Needs a phase 3 trial but could be an option if needing to avoid prednisone ex osteoporosis, DM, etc. abst#1107 #ACR22 @RheumNow https://t.co/OgcgslwaB5

RT @synovialjoints: ⇧ brain functional connectivity to the insula between the mid-posterior IC & brain areas invol

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⇧ brain functional connectivity to the insula between the mid-posterior IC & brain areas involved in sensory (thalamus), learning/affective (parahippocampal gyrus), cognitive (prefrontal cortex) pain modulation in PsA. Sunzini F Abs#2256 https://t.co/5TUcOacuIS #ACR22 @RheumNow https://t.co/7IqLYzzpyA
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MRI Spinal Lesions in Patients Without MRI or Radiographic Lesions in the Sacro… https://bit.ly/3UAj6Nk

RT @RichardPAConway: Figueroa Parra @AliDuarteMD et al. Multimorbidity in SLE. Higher at classification - due to non-SLE

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RichardPAConway
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Richard Conway
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Figueroa Parra @AliDuarteMD et al. Multimorbidity in SLE. Higher at classification - due to non-SLE assoc. SLE-assoc drive increased accumulation over time but non-SLE assoc also increased @RheumNow #ACR22 Abstr#2091 https://t.co/6IyhovSNYA https://t.co/qmYfoqCTtz
Links
Burden and Incidence of Multimorbidity in Systemic Lupus Erythematosus in a Com… https://acrabstracts.org/abstract/burden-and-incidence-of-multimorbidity-in-sys…

RT @RichardPAConway: Kavanaugh et al. TYK2i deucravacitinib in PsA. Nice breakdown of MDA and its components over 16 wee

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Richard Conway
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Kavanaugh et al. TYK2i deucravacitinib in PsA. Nice breakdown of MDA and its components over 16 weeks. MDA achieved 23-24% with deucravacitinib at 16 weeks vs 8% with placebo @RheumNow #ACR22 Abstr#2136 https://t.co/9IG8CeZzMh https://t.co/Vg8E20y7Z8
Links
Deucravacitinib, an Oral, Selective Tyrosine Kinase 2 Inhibitor, in a Phase 2 T… https://acrabstracts.org/abstract/deucravacitinib-an-oral-selective-tyrosine-ki…
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