IL-17is demonstrate efficacy in SpA tx Comparable with TNFis & JAKis in terms of achieving ASAS40 response rates IL

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IL-17is demonstrate efficacy in SpA tx Comparable with TNFis & JAKis in terms of achieving ASAS40 response rates IL-17is are generally well-tolerated w/⬇️TB risk (very important tx consideration esp in Asia) But watch out for candidal infx, IBD exacerbation @RheumNow #APLAR25 https://t.co/rSUJlZOhKV

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https://x.com/RHEUMarampa/status/1964520022430413290/photo/1

16 September 2025

SARD-ILD and serious infection risk: The elephant in the room

Interstitial lung disease (ILD) remains one of the largest unmet clinical needs across many systemic autoimmune rheumatic diseases (SARD). Clinicians are already keenly aware of the complexity of patients with SARD-ILD. The “elephant in the room” for all these issues: serious infection.

ILD and Mortality in Systemic Autoimmune Rheumatic Diseases

16 September 2025

Equal Safety of JAK Inhibitors and TNF Inhibitors

JAMA has published a systematic review and meta-analysis of head-to-head studies showing there was no meaningful difference in safety events observed when taking either JAK inhibitor (JAKi) vs TNF antagonist (TNFi) therapies for the treatment of immune-mediated inflammatory diseases (IMIDs).

Evidence of immune ageing detected at the earliest stages of RA. Study of 69 controls, 32 CSA, 44 undiff. arthritis (U

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RheumNow

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Evidence of immune ageing detected at the earliest stages of RA. Study of 69 controls, 32 CSA, 44 undiff. arthritis (UA), 23 early RA, & 56 DMARD naive RA. UA & CSA had reduced naive CD4 T cells. Th17, Tregs &7 senescent T cells, were only seen once RA was established. https://t.co/c1wiA5gvM5

Target trial emulation looked at CV (MACE) events in 18,120 propensity score–matched adults with gout starting allopur

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RheumNow

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Target trial emulation looked at CV (MACE) events in 18,120 propensity score–matched adults with gout starting allopurinol who were given NSAIDs or colchicine for prophylaxis. MACE & CV death were signif. higher w/ NSAIDs vs Colchicine (HRs of 1.56 and 2.50), respectively. https://t.co/0T8slmPBng

Hospital for Special Surgery (HSS) reports that ear acupuncture applied during hip replacement surgery reduces pain and

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RheumNow

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Hospital for Special Surgery (HSS) reports that ear acupuncture applied during hip replacement surgery reduces pain and lessens opioid use over the weeks to follow. https://t.co/lOrwb1DzW5 https://t.co/6rkHNTwaAl

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Three HSS Studies Presented at ESRA Annual Meeting Show that Ear Acupuncture Du… https://buff.ly/EiQ359A

RCT of 800 adults w/ Chronic LBP, acupuncture (AP) was compared usual care or AP +/- added maintenance found that acup

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RheumNow

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RCT of 800 adults w/ Chronic LBP, acupuncture (AP) was compared usual care or AP +/- added maintenance found that acupuncture improved pain-related disability at 6 months and 12 months, with no statistically discernible benefit of additional maintenance sessions. https://t.co/suy09fGxxI

SLE and Osteoporosis Systemic Lupus Erythematosus (SLE) is a multisystem autoimmune disease that can present with a va

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RheumNow

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SLE and Osteoporosis Systemic Lupus Erythematosus (SLE) is a multisystem autoimmune disease that can present with a variety of signs and symptoms and organ involvement. Comorbidities further complicate the disease course that may lead to poor health-related quality of life and https://t.co/8ZmtLjzbqA

SMART study - Single vs. Split Dose Methotrexate in RA Split dose weekly, oral methotrexate (MTX) was shown to be supe

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RheumNow

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SMART study - Single vs. Split Dose Methotrexate in RA Split dose weekly, oral methotrexate (MTX) was shown to be superior to single dose MTX in treating active rheumatoid arthritis (RA) patients. https://t.co/JN5wPGNjao https://t.co/lizsrtVHwf

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SMART study - Single vs. Split Dose Methotrexate in RA | RheumNow https://buff.ly/AIPUFjK

Topics

IL-17is demonstrate efficacy in SpA tx Comparable with TNFis & JAKis in terms of achieving ASAS40 response rates IL

SARD-ILD and serious infection risk: The elephant in the room

ILD and Mortality in Systemic Autoimmune Rheumatic Diseases

Evidence of immune ageing detected at the earliest stages of RA. Study of 69 controls, 32 CSA, 44 undiff. arthritis (U

Target trial emulation looked at CV (MACE) events in 18,120 propensity score–matched adults with gout starting allopur

Hospital for Special Surgery (HSS) reports that ear acupuncture applied during hip replacement surgery reduces pain and

RCT of 800 adults w/ Chronic LBP, acupuncture (AP) was compared usual care or AP +/- added maintenance found that acup

SLE and Osteoporosis Systemic Lupus Erythematosus (SLE) is a multisystem autoimmune disease that can present with a va

SMART study - Single vs. Split Dose Methotrexate in RA Split dose weekly, oral methotrexate (MTX) was shown to be supe

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