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9 April 2025

Pregnancy-Related Deaths in the US

A CDC cross-sectional national study showed an increase in pregnancy-related deaths in the US from 2018 to 2022, with highest rates among American Indian, Alaska Native women, and non-Hispanic Black women. 

9 April 2025
Yoga vs Strengthening Exercise in Knee Osteoarthritis

A randomized clinical trial in knee osteoarthritis (KOA) patients showed both yoga and strengthening improved knee pain over 12 weeks, with no difference between groups.

There is limited evidence on the comparative effectiveness of yoga and strengthening exercises in managing knee osteoarthritis (OA).

This single-center enrolled adults (> 40 years or older) with knee OA and knee pain (>40/100); patients were randomized 1:1 to the yoga and strengthening exercise groups. The primary outcome was improvement in the VAS pain score over 12 weeks.

Korean insurance claims study (2008–2021) 183,212 psoriasis & PsA pts, found Biologic Rx assoc w/ lower risk of ne

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Korean insurance claims study (2008–2021) 183,212 psoriasis & PsA pts, found Biologic Rx assoc w/ lower risk of new-onset & recurrent MACEs vs phototherapy (adj HR, 0.45 & 0.34). Nonbiologic systemic Rx lowered MACE risk (v photoRx) only in pts w/ prior Hx MACE (0.79) https://t.co/08wNm1AbpC

Does DMARD Rx affect neurocognitive function in older pts? bDMARDs targeting TNF-α & IL-6 may mitigate neuroinfla

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Does DMARD Rx affect neurocognitive function in older pts? bDMARDs targeting TNF-α & IL-6 may mitigate neuroinflammation & preserve cognitive function. But, cognitive impact of csDMARDs (MTX) is complex, w/ conflicting reports on its role in vascular dementia. https://t.co/6uMmOOdRoF

Mindfulness and CBT improve chronic low back pain Behavioral interventions were associated with reduced pain and daily

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Mindfulness and CBT improve chronic low back pain Behavioral interventions were associated with reduced pain and daily opioid use and improved function and quality of life for up to 12 months among adults with opioid-treated chronic low back pain, according to a new randomized https://t.co/e4jLNwNBy3

185 children with SLE (cSLE) were analyze for long-term outcomes. 38 (20.54%) had serositis. Pts w/ serositis were you

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185 children with SLE (cSLE) were analyze for long-term outcomes. 38 (20.54%) had serositis. Pts w/ serositis were younger, had more Dz activity, acomorbidities, & mortality. Having both serositis and ESRD increased risk of poor 20 Yr survival. https://t.co/tnYgg6MNXp https://t.co/zJor1oTFfD
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Serositis as an indicator of poor prognosis in pediatric systemic lupus erythem… https://buff.ly/GG1zJWk

EMA has approved upadacitinib (Rinvoq) for use in the EU to treat adult patients with giant cell arteritis (GCA) - appro

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EMA has approved upadacitinib (Rinvoq) for use in the EU to treat adult patients with giant cell arteritis (GCA) - approval is based on data from the Phase 3 SELECT-GCA trial demonstrating sustained remission and key secondary endpoints https://t.co/ycPNuB8C8y https://t.co/MCJNltn8Lj
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AbbVie Announces European Commission Approval of RINVOQ® (upadacitinib) for the… https://buff.ly/MWV4DOg

An Epidural Letdown (4.4.2025) Dr. Jack Cush reviews the news and journal reports from this past week on https://t.co/V

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An Epidural Letdown (4.4.2025) Dr. Jack Cush reviews the news and journal reports from this past week on https://t.co/V10S4oVFsv. https://t.co/YDxQWukJ5U https://t.co/Pr7tG5rU0R
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Danish registry study of 1431 AAV pts ((median age: 69 yrs, 52M; F/U 4.8 yrs) shows AAV had more LVH (17% vs 12%), S

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Danish registry study of 1431 AAV pts ((median age: 69 yrs, 52M; F/U 4.8 yrs) shows AAV had more LVH (17% vs 12%), ST-T (10% vs 7%), aFib (9.6% vs 7.5%), QTc prolong (6% vs 3.6%). Only AAV w/ major ECG abnls had incr risk of CV mortality [HR 1.99; 1.49-2.65) https://t.co/OB8b9pC6kw
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