To promote broader avail. of biosimilars in EU, EMA has proposed a new path for new biosimilars, omitting comparative cl

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To promote broader avail. of biosimilars in EU, EMA has proposed a new path for new biosimilars, omitting comparative clinical trial data, as long as biosimilar shows structural & functional comparability, w/ pharmacokinetic & interaction data (relative to reference product) https://t.co/24aTCuDwdO

Joint Implant Metals May Be Leaking Patients with metal-containing joint replacements had significantly higher concent

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RheumNow

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Joint Implant Metals May Be Leaking Patients with metal-containing joint replacements had significantly higher concentrations of cobalt in their cerebrospinal fluid (CSF) relative to patients without arthroplasties, researchers reported. https://t.co/ubDhWqtTSL https://t.co/GjMnog8mcJ

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Joint Implant Metals May Be Leaking | RheumNow https://buff.ly/hArWq3D

1st Line Biologics vs. csDMARDs in Adult Still's Disease A German multicentre, retrospective study assessed the first-

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RheumNow

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1st Line Biologics vs. csDMARDs in Adult Still's Disease A German multicentre, retrospective study assessed the first-line efficacy of biologics and conventional synthetic DMARD therapy in patients with adult-onset Still's disease (AOSD) and found biologic agents were https://t.co/EeSuBiYx5Q

Review article shows that in psoriasis pts, adding #MTX to TNFi increases efficacy, but there is limited data on adding

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Review article shows that in psoriasis pts, adding #MTX to TNFi increases efficacy, but there is limited data on adding MTX to either IL-17 or IL-23. But in Psoriatic Arthritis (PsA), adding MTX provides no added efficacy compared to biologic monotherapy https://t.co/FiSFIjpsXo https://t.co/ComFg253u9

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Role of methotrexate in biologics use with psoriasis and... : Dermatologica Sin… https://buff.ly/4wxAvRy

NIH Complimentary Medicine overview of Music Therapy - preliminary research suggests that music interventions may be hel

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RheumNow

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NIH Complimentary Medicine overview of Music Therapy - preliminary research suggests that music interventions may be helpful for anxiety, depression, pain control, dementia, multiple sclerosis, Parkinson’s disease, etc https://t.co/UGsfT7lITQ https://t.co/DrJm4JdEuY

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Music and Health: What You Need To Know https://buff.ly/DQuAVFO

EMA approved a record 28 biosimilars in 2024 for cancer, osteoporosis, macular degeneration, and immune-related diseases

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EMA approved a record 28 biosimilars in 2024 for cancer, osteoporosis, macular degeneration, and immune-related diseases like plaque psoriasis, ulcerative colitis, and Crohn’s disease https://t.co/NNzKRalLvF https://t.co/nfX082a7ON

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EMA approved a record 28 biosimilars in 2024 https://buff.ly/jcdFNeY

2 April 2025

Upadacitinib for Giant-Cell Arteritis - A Phase 3 Trial

The NEJM has published a randomized controlled trial in giant-cell arteritis (GCA) patients, demonstrating significant efficacy and safety of upadacitinib (UPA), given as 15 mg daily, as compared to placebo.

A total of 209 GCA patients (70% had had new onset GCA) were randomized in a 2:1:1 ratio, to receive upadacitinib at a dose of 15 mg or 7.5 mg once daily in combination with a prespecified 26-week glucocorticoid (GC) taper or placebo.

2 April 2025

Diagnostic delays and Undertreatment of Psoriatic Arthritis

New research from the University of Bath in the UK reveals delayed diagnosis and undertreatment of psoriatic arthritis often results in irreversible damage to joints.

Delays in diagnosing and treating psoriatic arthritis – a common inflammatory disorder affecting 112 in every 100,000 adults – are causing irreparable damage to people’s health. This damage could be avoided by catching the condition earlier and treating it effectively, according to research led by scientists in the Department of Life Sciences at the University of Bath in the UK.

Consensus on Bone Turnover Biomarkers in Osteoporosis A new consensus paper, published by the European Society for Cli

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Consensus on Bone Turnover Biomarkers in Osteoporosis A new consensus paper, published by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO), the International Osteoporosis Foundation (IOF), and the https://t.co/lq1odNBLdZ

Consensus Against Interventional Injections for Chronic Spinal Pain BMJ has published a clinical practice guideline re

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Consensus Against Interventional Injections for Chronic Spinal Pain BMJ has published a clinical practice guideline resulting from the work of an international, multidisciplinary panel addressing chronic spine pain (≥3 months duration) not associated with cancer or https://t.co/PfXM210PsZ

Topics

To promote broader avail. of biosimilars in EU, EMA has proposed a new path for new biosimilars, omitting comparative cl

Joint Implant Metals May Be Leaking Patients with metal-containing joint replacements had significantly higher concent

1st Line Biologics vs. csDMARDs in Adult Still's Disease A German multicentre, retrospective study assessed the first-

Review article shows that in psoriasis pts, adding #MTX to TNFi increases efficacy, but there is limited data on adding

NIH Complimentary Medicine overview of Music Therapy - preliminary research suggests that music interventions may be hel

EMA approved a record 28 biosimilars in 2024 for cancer, osteoporosis, macular degeneration, and immune-related diseases

Consensus on Bone Turnover Biomarkers in Osteoporosis A new consensus paper, published by the European Society for Cli

Consensus Against Interventional Injections for Chronic Spinal Pain BMJ has published a clinical practice guideline re

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