PAFLAR Guidelines for Polyarticular Juvenile Idiopathic Arthritis The Pediatric African League against Rheumatism (PAF

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PAFLAR Guidelines for Polyarticular Juvenile Idiopathic Arthritis The Pediatric African League against Rheumatism (PAFLAR) initiative has published its guidelines for the diagnosis and treatment of polyarticular juvenile idiopathic arthritis (pJIA). https://t.co/4MbU8ZDLZf https://t.co/o3Oym9ff0f

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PAFLAR Guidelines for Polyarticular Juvenile Idiopathic Arthritis | RheumNow https://buff.ly/YFDBHs7

21 March 2025

ERA, APPs, & Alpha GAL (3.21.2025)

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com. Listen in for 2 new case questions - Ask Cush Anything.

ERA, APPs, & Alpha GAL (3.21.2025)

Axial Involvement in Psoriatic Arthritis Analysis of a Greek Psoriatic Arthritis (PsA) cohort shows that nearly one qu

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Axial Involvement in Psoriatic Arthritis Analysis of a Greek Psoriatic Arthritis (PsA) cohort shows that nearly one quarter of patients have axial involvement, and among them, ∼30% have isolated spinal axPsA and nr-axSpA, respectively. https://t.co/MmRMlEp7zR https://t.co/ZAbfpIWwRM

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Axial Involvement in Psoriatic Arthritis | RheumNow https://buff.ly/sbcawuk

The FDA has approved guselkumab(Tremfya) for both subcutaneous (SC) and intravenous (IV) induction therapy treatment of

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The FDA has approved guselkumab(Tremfya) for both subcutaneous (SC) and intravenous (IV) induction therapy treatment of adults with moderately to severely active Crohn’s disease (CD). It is the only IL-23 inhbitor available for SC and IV use in CD https://t.co/ekXRVOwNnS https://t.co/6zveRR5WjD

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U.S. FDA approves TREMFYA® (guselkumab), the first and only IL-23 inhibitor off… https://buff.ly/MwWnOfQ

Systematic review of colchicine and pregnancy in #FMF pts included 25 studies. Miscarriage was not increased w/ colchic

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Systematic review of colchicine and pregnancy in #FMF pts included 25 studies. Miscarriage was not increased w/ colchicine in FMF (RR 0.87). Birth defects were similar to unexposed pts (range 0.6% to 4.0%). Colchicine showed no effects (men/women) on fertility. 1 study reported… https://t.co/axiH9jhEJr https://t.co/oBpew71fZw

20 March 2025

Disease activity during Pregnancy in Rheumatoid arthritis and Spondyloarthritis

A prospective French study of rheumatoid arthritis (RA) or spondyloarthritis (SpA) patients showed that most maintained stable disease activity during pregnancy, but over one-third flared and required major changes in treatment.

The aim of this study was to analyze disease activity and relapse during pregnancy in women with RA and SpA. Data was drawn from the multicentre prospective GR2 study that enrolled consecutive pregnant women with RA or SpA (between 2014 to 2022) who had at least two prenatal visits (including one in the first trimester).

20 March 2025

Increasing Prevalence of Osteoporosis

Research published in Osteoporosis International studied NHANES data showed increasing trends in osteoporosis in the United States of America. The key findings showed statistically significant results.

Spatial transcriptomic profiling on pre- and post-Rx synovial tissue Bxs from RA - Tx naive pts on DMARDs or adalimumab.

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Spatial transcriptomic profiling on pre- and post-Rx synovial tissue Bxs from RA - Tx naive pts on DMARDs or adalimumab. Rx refractory patients had high expression of COMP, and fibroblast TGFβ signaling driving synovial tissue fibrosis https://t.co/1xFVvoddCD https://t.co/kYvhyX8VuS

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Spatial patterning of fibroblast TGFβ signaling underlies treatment resistance … https://buff.ly/ihQcp4h

Mizoribine Effective in Lupus Nephritis A randomized clinical trial has shown that oral mizoribine, a common immunosup

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Mizoribine Effective in Lupus Nephritis A randomized clinical trial has shown that oral mizoribine, a common immunosuppressant in Japan, was noninferior to intravenous cyclophosphamide (CTX) as induction therapy in patients with active lupus nephritis. https://t.co/OS3yaJlEm7 https://t.co/1YcyfarF09

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Mizoribine Effective in Lupus Nephritis | RheumNow https://buff.ly/lSsZELd

Topics

PAFLAR Guidelines for Polyarticular Juvenile Idiopathic Arthritis The Pediatric African League against Rheumatism (PAF

ERA, APPs, & Alpha GAL (3.21.2025)

ERA, APPs, & Alpha GAL (3.21.2025)

Axial Involvement in Psoriatic Arthritis Analysis of a Greek Psoriatic Arthritis (PsA) cohort shows that nearly one qu

The FDA has approved guselkumab(Tremfya) for both subcutaneous (SC) and intravenous (IV) induction therapy treatment of

Systematic review of colchicine and pregnancy in #FMF pts included 25 studies. Miscarriage was not increased w/ colchic

Spatial transcriptomic profiling on pre- and post-Rx synovial tissue Bxs from RA - Tx naive pts on DMARDs or adalimumab.

Mizoribine Effective in Lupus Nephritis A randomized clinical trial has shown that oral mizoribine, a common immunosup

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