JAMA Dermatology reports a retrospective cohort study from Johns Hopkins reviewing mimic of dermatomyositis (DM), suggesting that DM and especially clinically amyopathic DM (CADM) are commonly and initially misdiagnosed as inflammatory skin disease (ISD).

The study was undertaken to evaluate misdiagnosis patterns and the clinical implications of those with DM and CADM.

Study included adults with confirmed DM or CADM, seen between 2005 and 2023. Duration of misdiagnosis was defined as time between first ISD diagnosis and DM or CADM confirmation. 

A study from the FDA's adverse event reporting system (FAERS or Medwatch) database identified cases of drug induced systemic lupus erythematosus (SLE) in patients receiving tumor necrosis factor-α (TNF-α) inhibitors - a paradoxical reaction to common antiinflammatory biologic agents.