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Treatment of Rheumatoid Arthritis

In starting a new biologic agent in RA, when do you expect to see a good response?

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Which advancement had the greatest impact on rheumatoid arthritis patients?

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What is most disappointing regarding the care of RA patients?

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What drug have you used LESS over the last 20 years?

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In the last 20 years what drug are you using MORE of in RA?

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What RA finding most incites you to use aggressive therapies?

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How has YOUR use of biologic/new therapies changed in the last 20 years?

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RA patients who have failed at least 1 biologic (e.g., TNFi), what factors guide your next biologic choice?

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How many TNF inhibitors will you try before you use another MOA drug?

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What is your gender?

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How many years have you been out of Rheumatology fellowship?

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US CDC study of age-standardized mortality rate (ASMR) from 1990-2020, there were 39,496 deaths related to scleroderma

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Dr. John Cush
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US CDC study of age-standardized mortality rate (ASMR) from 1990-2020, there were 39,496 deaths related to scleroderma (SSc) & and 5,163 from SSc w/ renal failure. Deaths lower in males (22%) than females w/ renal failure (78%). Mortality rate of SSc w? renal failure was https://t.co/OT3BHt3E85

Congrats to Barbara Anne Eberhard, MD, she has been awarded with the James T. Cassidy Award from the American Academy of

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Dr. John Cush
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Congrats to Barbara Anne Eberhard, MD, she has been awarded with the James T. Cassidy Award from the American Academy of Pediatrics (AAP). For her dedication to research/leadership in pediatric rheumatology. She is at Northwell Health’s Cohen Children’s Medical Center & Feinstein https://t.co/USGajXCMLD

40 kids w/ Psoriasis compared to 40 juvenile PsA pts. Those w/ jPsA were more likely to be: - Obese/overweight (80 vs 1

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Dr. John Cush
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40 kids w/ Psoriasis compared to 40 juvenile PsA pts. Those w/ jPsA were more likely to be: - Obese/overweight (80 vs 17.5%) - passive smoking (37.5 vs (25%) - Signif higher ESR and CRP (P < 0.001) - Nail PsO (65 vs 22%) https://t.co/3uBHnxZYC2 https://t.co/rW48EQta2s

RA Lung Disease Portends Poor Outcomes A retrospective Harvard affiliates study shows that rheumatoid arthritis (RA) p

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Dr. John Cush
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RA Lung Disease Portends Poor Outcomes A retrospective Harvard affiliates study shows that rheumatoid arthritis (RA) patients with lung disease have higher mortality, especially respiratory and infection-related mortality than those without lung disease (LD). https://t.co/13h2u26ecb
Practical management of rheumatic immune-related adverse events with immune checkpoint inhibitors
Joint Bone Spine has published a full read review of the management of immune-related adverse events (irAEs) in patients receiving Immune checkpoint inhibitors (ICIs) for cancer.
Subclinical Synovitis Among Psoriasis Patients

A systematic review shows that imaging can be used to detect subclinical synovitis among patients with psoriasis and may identify individuals at risk for future psoriatic arthritis.

A meta-analysis of 12 cross-sectional and case-control studies, synovitis was 2.5 times more likely to be detected using ultrasonography and magnetic resonance imaging among patients with psoriasis compared with controls. Synovitis prevalence was higher among patients with psoriatic arthritis than those with psoriasis, but the difference was not statistically significant.

Pesticides and Rheumatoid Arthritis? Women exposed to pesticides through farm work or as farmers' wives face increased

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Dr. John Cush
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Pesticides and Rheumatoid Arthritis? Women exposed to pesticides through farm work or as farmers' wives face increased risk for developing rheumatoid arthritis (RA), a new analysis of Agricultural Health Study (AHS) data indicated. https://t.co/ISddKbnxMY https://t.co/E5tpX5D70X

Diminishing trend in serious infections assoc w/ TNFi use in inflammatory arthritis over the years. ICEBIO study 1387 Rx

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Dr. John Cush
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Diminishing trend in serious infections assoc w/ TNFi use in inflammatory arthritis over the years. ICEBIO study 1387 Rx w/ 1st TNFi 2003–2018 (vs 6936 comparators. Over tme the SI rate dropped 52% (IRR 0.48; 0.25–0.94), but not for controls (Abx use stable) https://t.co/jDsKlCrd0p

New ICD-10 Diagnostic Code -- R76.81 -- for ’At-Risk RA’ (AKA Clinically suspect arthralgia or Pre-clinical RA); t

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Dr. John Cush
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New ICD-10 Diagnostic Code -- R76.81 -- for ’At-Risk RA’ (AKA Clinically suspect arthralgia or Pre-clinical RA); this applies to pts w/ abnormal RF or ACPA without having RA. Thanks to Dr. Kevin D. Deane for leading this effort. https://t.co/14I6RCZrXb https://t.co/YxTwPB0YDQ
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