Cochrane review of Stem cell transplantation in systemic sclerosis (3RCTs w/ 125 pts). Non‐myeloablative & myeloablative selective HSCT had moderate evidence for improved survival, skin thickness & function. But these had high Serious AE rates. https://t.co/VKciXY0klN https://t.co/LdMu3RrlZK

Hyaluronic Acid Knee Injections Equivalent to Placebo In the United States, where over $300 million is spent annually on intraarticular hyaluronic acid injections, yet another study shows such therapy to be no better than placebo. https://t.co/NwJkyECfgM https://t.co/qGLQMWjQG4

Charcot (neuropathic) arthropathy of elbow due to Syringomyelia - review of 50 pts. Median age 45 yrs, 2/3 isolated elbow arthritis; other joints: shoulder > wrist > MCPs/IPs. 2/3 had Chiari malformations, sensory/motor deficits, or ulnar neuropathy https://t.co/2hEArpbL8p https://t.co/MK4VTzSSRB

Review of VTE risk with JAK inhibitors - Tofacitinib: 10mg or 5 mg bid - PE rates 0.5 & 0.3/100PY; higher w/ risk factors, VTE 0.35/100PY - Baricitinib: IR of DVT/PE was 0.5/100PY - Filgotinib: 200mg VTEs 0.2/100PY Most VTE occured in LT extension of RCT https://t.co/xvf0kQUMel https://t.co/Bj6fmkktP7

Dr. Jack Cush delivers this weeks rheumatology "weather report" with the best and least of news and journal articles from the past week on RheumNow. Are you a fan of our podcast? Please rate, like and review us wherever you get your podcast. https://t.co/uj6QF3EqlU https://t.co/lFpoRfkEqU

Melatonin Use Growing, Inappropriate & Potentially Unsafe With nearly 1/3 of adults, adolescents and children having sleep difficulties, many resort to using melatonin. But is it effective, safe and warranted? https://t.co/8TA76yAbwr https://t.co/ADYklo0yMz

Olokizumab, another IL-6 Inhibitor for RA This week's NEJM has published the efficacy results of a large phase 3 trial of olokizumab, a humanized monoclonal antibody that directly targets interleukin-6 (IL-6) in patients with rheumatoid arthritis (RA). https://t.co/VMz8xzffiZ https://t.co/eaA4CUWvrv

Hyaluronic Acid Knee Injections Equivalent to Placebo In the United States, where over $300 million is spent annually on intraarticular hyaluronic acid injections, yet another study shows such therapy to be no better than placebo. https://t.co/1pSVr3VI4t https://t.co/DvFN7WQdTp

Bullous Systemic Lupus Erythematosus (BSLE) BSLE is a rare blistering cutaneous manifestation of systemic lupus erythematosus (SLE). As goes SLE, bullous disease typically affects women, especially those of African descent. https://t.co/TBr7pGXjZ5 https://t.co/aq5dX3wQPX

Record Use of Marijuana and Hallucinogens in Young Adults The NY Times reports that a recent survey of drug use indicates that daily consumption of marijuana among young adults nearly doubled in the last decade. https://t.co/Dvj4nUNdtg https://t.co/BRkq8nb5sz