Tweets
Dr Eric Ruderman presents on rare Stiff Man syndrome at #RWCS2022 https://t.co/n7IV8UVI2N
Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
EMA has posted its intent to review the safety of JAK inhibitors used to treat several chronic inflammatory disorders (RA, PsA, JIA, AS, UC, atopic dermatitis) based on the release of the Pfizer tofacitinib A3921133 study https://t.co/loG7zWBWHs
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Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
Mortality of Cryoglogulinemia has declined between 1999 and 2018 freom 0.4 deaths per million to 0.19. Cryo found in 39% of HCV(2009–2013) down to 26% (2014–2018). Prevalence and deaths dropped witn introduction of HCV antiviral Rx https://t.co/h9rL1ftI0n
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Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
Challenges in Lupus:
-Mortality greatest in 1st yr
-Dx Delays 6.4 yrs
-Long-term complications increased 50 fold
-Steroids worsen long-term outcomes
-Health care costs increased 3 to 5 years prior to Dx
-Mean delay in drug starts after Dx =177 days https://t.co/QUbsIQtcRa https://t.co/zAMUp99ecg
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Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
Olumiant (baricitinib) studies in Lupus halted by Lilly due to mixed results in phase 3 trials. While the BRAVE-1 study showed 4-mg BARI meeting primary endpoint at 52 weeks; the Brave-II failed to do same & failed key secondary endpoints https://t.co/XBmo15UCYl
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Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
Lupus international cohort study of 1460 HCQ pts showed that SLE flares were increased with dose reduction (aHRs 1.20;CI 1.04 to 1.38) and HCQ discontinuation (aHR 1.56; 1.31 to 1.86), higher with low educational levels after HCQ D/C https://t.co/fO4fBtrFYo
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Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
Fatigue in Early RA registry - study of n = 1236 pts w/ Dz duration 11 mos. The prevalence rates of fatigue was 44% and severe fatigue 19% and was stable over 3 yrs. Greater fatigue in women, high pain, mental Dz, function; BUT NOT SJC or ESR https://t.co/hEgPbsAqYZ
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Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
Taiwan study of 12,786 pre-dialysis advanced CKD patients with gout shows that use of febuxostat or allopurinol was assoc w/ a reduced sepsis/infection risk - most w/ FEB (HR, 0.68; 0.52–0.87), but no signif difference in MACE or CVA https://t.co/zp7JLwzah8
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Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
Join Dr. Ronan Kavanagh for an incredible STEP Session at #RNL2022, where he will discuss The Jazz of Rheumatology.
Register today!
https://t.co/hMzdpN327q https://t.co/uHYC9VV1kp
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Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
Round up of last week's QD Clinics:
-Steroid Weaning
-Diagnosing Neuropsychiatric Lupus
- Not the Same Ol’ Lecture
- Your Next Follow-up Visit is When?
QD Clinic is sponsored by RheumNow Live
https://t.co/9U1wcbIMs4 https://t.co/HjyyGtbe4r
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Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
UK Biobank case control study of 15 871 pts with Gout and COVID. Gout associated with diagnosis of COVID-19 (OR 1·20; CI 1·11–1·29) but not with risk of COVID-19-related death in the cohort of patients diagnosed with COVID-19 (1·20, 0·96–1·51). https://t.co/dN5YnIqhzD
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Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
Should we use colchicine in COVID-19? Mainly mixed results; not likely effective in sick hospitalized patients but may have utility in early infections https://t.co/wecWjSIbEG
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Dr. John Cush @RheumNow ( View Tweet )
4 years 5 months ago
