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WHO global safety database shows increased risk of DVT & PE with tofacitinib & baricitinib, who were likely to be older with preexisting VTE risk. In EU, TOFA risk for DVT/PE was OR 2.3; BARI risk was OR 3.4. No VTE risk for BARI in US, TOFA 2.0 VTE risk https://t.co/PUBUzfrydn

Dr. John Cush RheumNow( View Tweet)

2 weeks 4 days ago
Early COVID 1255 patients In Wuhan, China - median age 64 yrs; 53 male: 63% w/ chronic comorbidities. There were 17 autoimmune pts w/ COVID () - median age 64; 83% female; only 1 admitted to ICU and one died. 10 stopped DMARDS & 5 their Dz worsened https://t.co/1KgU9tYUqV

Dr. John Cush RheumNow( View Tweet)

2 weeks 4 days ago
NGF inhibitor Tanuzemab (TNZ) phase III study in patients with low back pain - H2H against placebo and tramadol. At 16 wks, ≥50% improvement in LBPI was 37%, 43% TNZ 5mg and 46% TNZ 10mg (Odds ratio [95% CI] vs placebo = 1.45 [1.09, 1.91; P=0.0101]). https://t.co/3DvUHtxcqk

Dr. John Cush RheumNow( View Tweet)

2 weeks 4 days ago
The 5 states with the highest slope of case increasing, per million population, June 20th 1. Arizona (way out in front) 2. South Carolina 3. Florida 4. Texas 5. Oklahoma (pre-rally) https://t.co/M1PsBgmhJb
Eric Topol EricTopol( View Tweet)
2 weeks 4 days ago
#EULAR2020 Round-Up w/ Drs. Kavanaugh & Cush. Watch it on RheumNow https://t.co/5v9BTuLrPX or listen to the podcast on iTunes https://t.co/FHJv01AAbC or on Android Sound Cloud https://t.co/nb7iXdRMMb

Dr. John Cush RheumNow( View Tweet)

2 weeks 5 days ago
RheumNow Podcast is Up! New FDA approvals for secuminumab, canakinumab, risk of GI perforations, tocilizumab in COVID, Weaning DMARDs/Biologics and Blacks with AS. Watch here>> https://t.co/2fTQPJ5iSr Listen to the podcast on Soundcloud>> https://t.co/uPklKQEauE

Dr. John Cush RheumNow( View Tweet)

2 weeks 5 days ago
Study of 260 pts with cutaneous lupus shows higher CLASI (skin activity) scores were associated with smoker, higher CRP, and chronic CLE disease https://t.co/X1eJel9CLP

Dr. John Cush RheumNow( View Tweet)

3 weeks ago
Congratulations to Christopher Buckley, Kennedy Professor of Translational Rheumatology at the University of Birmingham and Oxford, for being awarded the 2020 Carol Nachman prize for Rheumatology https://t.co/xis9RmsoCf

Dr. John Cush RheumNow( View Tweet)

3 weeks ago
African-Americans with Ank Spondylitis have worse disease compared to whites. Study of 10,990 AS patients shows AA to have high frequency of anterior uveitis, hypertension, diabetes, depression, and heart disease and higher ESR and CRP levels. https://t.co/YyLqlM85sD

Dr. John Cush RheumNow( View Tweet)

3 weeks 2 days ago
Measures to address Rheumatology Workforce shortages: 1) increase Rheum training programs; 2) expand use/utilization of NP, PA,pharmacists; 3) Telemedicine expansion; and 4) measures to reduce physician burnout https://t.co/oCE8ZxBpVv

Dr. John Cush RheumNow( View Tweet)

3 weeks 2 days ago
MMWR reports that hospitalizations were 6 times higher and deaths were 12 times higher when the COVID patient presented with comorbidities - the most common being cardiovascular disease (32%), diabetes (30%), and chronic lung disease (18%) https://t.co/JPynBcJYfR https://t.co/kiBEIV38Sg
Dr. John Cush RheumNow( View Tweet)
3 weeks 3 days ago
FDA has revoked it's emergency use authorization for hydroxychloroquine in COVID-19. "CQ and HCQ are unlikely to be effective in treating COVID-19 for the authorized uses .... (and)..in light of ongoing serious cardiac adverse events and other serious AE" https://t.co/TrzJQVzsv7

Dr. John Cush RheumNow( View Tweet)

3 weeks 3 days ago
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