Neoplasia and Autoimmune Disease Malignancy rivals cardiovascular disease as a leading cause of death in patients with systemic autoimmune diseases. Chronic inflammation and immune dysregulation can drive oncogenesis, while antitumor immune responses can trigger autoimmune https://t.co/uIsVl1N1hH

Switch or Cycle - Upadacitinib vs Adalimumab in Refractory RA After the first tumor necrosis factor inhibitor (TNFi) failure, patients with active rheumatoid arthritis (RA) responded by switching to upadacitinib, compared to cycling to a second TNFi, adalimumab. https://t.co/mEaUcBD2ZK

Mexico study of SLE mortality in kids. Betw 2000-23, SLE accounted for 637/280,334 child deaths. Females (80%) had 4X higher deaths than males (ASMR 0.13 vs 0.03). No consistent trend in time for mortality. https://t.co/gkoXG90nLx https://t.co/BB0JhTHFKf

A man spends 50 years teaching at MIT. He knows his time is running out. So he records one last lecture — everything he knows, distilled into a single hour. He died 5 months later. This is that lecture. The most important hour you'll watch this week. 👇 Bookmark it for later https://t.co/tRUH05ysSt

APR: Methotrexate Companion slide deck for the Advanced Practice Rheum: Methotrexate video, featuring Dr. Jack Cush. https://t.co/8422FKN4dq https://t.co/6gVS7dA8Gi

True or False: Low-dose aspirin given at giant cell arteritis diagnosis is associated with a lower risk of major adverse cardiovascular events. Put your answer to the test in the latest RheumIQ quiz at https://t.co/XLPVoyCbLB. https://t.co/C5CSwuv5mF

Study of 216 RA pts - Serum IL-8 independently assoc w/ RA Dz activity. CRP & IL-6 significantly associated w/ higher IL-8 levels, but RF & CCP did not. IL-8 also correlated w/ CV risk (SCORE2) & carotid intima media thickness https://t.co/aqUoAeXFFP https://t.co/ZW7OAx8YGK

Dental study from India assessed periodontal Dz (PD) in 170 RA vs 170 non-RA pts. RA had more PD, ^ESR, more mild PD (39% v 29%). DAS-28 correlated w/ PD severity. Pts w/ periodontitis had 3X ods of RA (OR = 2.9) /https://t.co/bvOnFzbRcd https://t.co/cSxfiIR4iS

Follow the Money (4.23.2026) Dr. Jack Cush follows the money and all the news that fits the Rheumatology Gab for this past week. https://t.co/nEWINTOw6L https://t.co/a4oZxqwYhv

True or False: The DESIR axSpA cohort study found a significant association between NSAID use and incident hypertension over 10 years. See if you got it right in the latest RheumIQ quiz at https://t.co/N5rfozh757. https://t.co/tkj0na3bkh

The impact oif obesity on the immune system. Through methylation, obesity imprints memory to CD4+ (helper) T cells, which can last for many years, and promotes immune system dysregulation and inflammation. @emboreports https://t.co/j2tASpZlE0 https://t.co/5CgUrsFZru

APR: Difficult to Treat RA Companion slide deck for the Advanced Practice Rheum: Difficult to Treat Rheumatoid Arthritis video, featuring Dr. Jack Cush. https://t.co/GXnTicNTL6 https://t.co/ojOsMZ4sA7

Are uveitis and psoriasis independently associated with greater spinal radiographic progression in ankylosing spondylitis? Test your knowledge in the latest RheumIQ quiz at https://t.co/N5rfozh757 https://t.co/PjY1iuLv0X

Danish registry study of truncal (2,260) vs superselective (3,810) vagotomy (1977-95) vs general popul. (10:1). Truncal incr. RA risk (aHR 2.62), but selective did not (aHR 1.05. Neither had effect on OA risk https://t.co/dqejtN9TwY https://t.co/R0OJZTxd5T 

Sun Pharma buys out Organon w/ $11.75 billion buyout. Both generated $6.2 billion in 2025 sales. Organon spun off from ‌Merck in 2021, specializes in women’s health and is top 7 in biosimilars. Sun is into dermatology, ophthalmology and oncology-dermatology. https://t.co/zb4hucTqCJ