Articles By Jack Cush, MD
Favorable Certolizumab Safety Profile in Pregnancy
Clowse and colleagues have published an extensive review of the certolizumab pegol (CZP) in pregnancy database, and found no evidence that CZP has a teratogenic effect or contributes to fetal harm when compared to the general population.
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RheumNow Week in Review -The Temporal Artery Biopsy Letdown (4.6.2018)
Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com. News on the cost of RA care, infections on planes, CV events and Sacroiliitis in IBD, NXP-2 antibodies and calcinosis and rituximab in myositis ILD patients.
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IL-6 Inhibition Most Effective in Polycyclic Systemic JIA
The German Autoinflammatory Disease (AID) registry has studied the effects of the IL-6 inhibitor tocilizumab (TCZ) in systemic juvenile idiopathic arthritis (sJIA) patients and shown a clinical response rate of 35% during the first 12 weeks, and inactive disease and/or remission (with medication)
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Rituximab May Halt ILD in Antisynthetase Syndrome Myositis
A multicenter study assessed patients with the antisynthetase syndrome (AS) and interstitial lung disease (ILD) and found that rituximab (RTX) therapy was associated with either improved or stable pulmonary outcomes in most.
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Lancet Tackles the Global Challenge of Low Back Pain
Lancet has several reports on low back pain (LBP) as a major problem worldwide, largely because of the aging population. Low back pain is the leading cause of disability worldwide.
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Cannabis Laws Lessen the Opioid Crisis
Three reports from JAMA Internal Medicine demonstrate favorable trends with less opioid use when cannabis became legal.
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Unmet Needs in Calcium Pyrophosphate Deposition Disease
Abhishek et al have written on the results of an international survey of crystal arthritis experts and identified the unmet needs regarding calcium pyrophosphate crystal deposition (CPPD) - research, classification, diagnosis and management.
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A Least Favored Patient
Sasha D just doesn’t like me. I’ve seen her four times in the clinic, and each visit was a tense battle of misunderstandings, with both of us leaving dissatisfied or worse. The failing wasn’t in the diagnosis, but rather the malalignment of our goals and inability to listen. Despite my efforts, my words, the diagnoses and treatment suggestions haven’t been well received.
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The RheumNow Week in Review -30 March 2018
Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com. News on drug regulatory decisions, fenofibrate and gout, Still's disease, TB and infection rates, SpA and hidradenitis suppurativa, and predicting methotrexate non-responders.
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NHANES: Trends in Calcium Supplements
The journal Bone reports that given excess calcium intake may not be entirely free from unintended health consequences, it's important to undestand trends in calcium supplement use.
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