Articles By Jack Cush, MD
Targeting CD11b as Treatment for Lupus
Researchers from Rush University Medical Center have reported in the March 6 issue of the Journal of Clinical Investigation that engagement of the integrin CD11b with a novel compound, may improved outcomes in patients iwth systemic lupus erythematosus (SLE).
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CDC Says 1 in 5 Have Arthritis
In the United States, doctor-diagnosed arthritis is a common and widespread chronic condition (1,2). Arthritis is a leading cause of disability (3) and is projected to affect 78.4 million adults by 2040.
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Non-Ischemic Heart Failure in Rheumatoid Arthritis
The current issue of the Journal of the American College of Cardiology reports on the relative risk of heart failure (HF) in rheumatoid arthritis (RA) and its relation to ischemic heart disease (IHD).
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TNF Inhibitor Therapy and the Risk of Anterior Uveitis Recurrence
The TNF inhibitor drug development trials have indirectly taught us that monoclonal antibody based TNFi was capable of retarding the recurrence of anterior uveitis (AU) in patients with ankylosing spondylitis (AS).
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Meta-analysis Reveals Numerous Pregnancy Complications Associated with Lupus
On the heels of the recently published EULAR recommendations for the management of pregnancy in patients with systemic lupus erythematosus (SLE) and the anti-phospholipid syndrome (APS) comes a new meta-analysis published in the Journal of Autoimmunity on pregnancy outomes in lupus.
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The RheumNow Week in Review – 3 March 2017
Dr. Cush reviews the highlights and news from the past week on RheumNow.com.
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Psychologic Impact of Rheumatoid Arthritis on Men
Arthritis Care & Research has reported the results of a study that analyzed the perceptions and attitudes of men afflicted with rheumatoid arthritis (RA). The results are drawn from a series of focus groups involving 22 men with RA.
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Novel Mechanisms for Rheumatoid Arthritis
The Journal of Leukocyte Biology has reported mechanisms whereby synovial CD4+ T cells producing IL-21 can contribute to the pathogenesis of RA by activating synovial fibroblasts.
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What You Don't Know
“It’s unbelievable how much you don’t know about the game you’ve been playing all your life.” - Mickey Mantle
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Ophthalmic Giant Cell Arteritis and the Risk of Stroke
Chronic inflammation is a well-known risk factor for cardiovascular disease and stroke.
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