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Articles By Jack Cush, MD

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Men and Blacks Undertreated for Osteoporosis

Using claims data from 36,965 patients in an Indiana database, researchers found women (OR 1.86) and non-black patients (OR 1.52) were more likely to be treated (p<0.001) for osteoporosis.

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Gut Dysbiosis in RA Reflects Activity, Serology and Response

Using a metagenome-wide association study (MGWAS) of fecal, dental and salivary samples from rheumatoid arthritis and healthy controls, Zhang et al showed that gut and oral microbiomes are highly concordant and that in RA there is a distinct dysbiosis with less Haemophilus spp.

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Is Morning Stiffness Important?

Morning stiffness? An oft-asked question, but does it have reliable discriminatory value?

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Not All Placebos are Equal: The Needle is Mightier than the Pill

Placebos are necessary to determine the “true effect” of any medical intervention. As such, they have become the cornerstone of evidence-based medicine, randomized controlled clinical trials and novel drug development.

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2015 Guidelines for Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing form of interstitial pneumonia, with poor survival rates of nearly 50% at 3 years.

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Psoriasis and Psoriatic Arthritis Have an Increased Risk of Gout

The frequency of gout among patients with psoriatic disease was studied in two cohorts of 98,810 patients from the Health Professionals Follow-up Study (1986-2010) and the Nurses' Health Study (1998-2010).

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What's Your Diagnosis? Truncal Rash, Arthritis and +ANA

An 80 year old woman complains of 3 months of rash on her back. It is modestly pruritic. The lesions are both annular and papular appearing over her back, torso and upper arms. She also complains of pain and swelling in her fingers.

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Tacrolimus Tops Other DMARDs as Induction Therapy for Lupus Nephritis

Metanalysis of nine clinical trials and 972 lupus patients examined the comparative efficacy of tacrolimus, mycophenolate (MMF) and cyclophosphamide (CYC) as induction therapy for lupus nephritis.

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Outcry Over the Cost of Drugs

Several news articles have addressed the rising concern by patients and physicians over the cost of newer drugs. This issue comes to a head as more than 100 oncologists from top cancer hospitals around the U.S.

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DSB: Drug Shortages July 2015

Several drugs continue to be in short supply, posing significant problems for patients. Foremost on this list is leflunomide (Arava) which is backordered for both 10 mg and 20 mg tablets.   Leflunomide Shortage

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