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Articles By Jack Cush, MD

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Adherence to ETN/MTX is Greater Than Triple DMARD Therapy

Rheumatoid management hinges on choosing your best therapies first.

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Right Knee Pain - What's Your Dx?

A 36 year-old white male butcher has right knee pain for 3 weeks. He noted a similar episode 5 years earlier and admits to a traumatic fall on that knee years ago. He denies fever, redness, warmth, other joints or other past medical problems. He only takes OTC ibuprofen prn. 

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Australia Allows Pharmacy Substitution with Biosimilars Without Notice

Biosimilars are copies of the biologic medicines used to treat inflammatory and immunologic conditions such as rheumatoid arthritis, multiple sclerosis and cancer- potentially at lower costs.

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Chikungunya Infection in Rheumatoid Arthritis Patients

Chikungunya virus (CKV) is an acute febrile illness caused by an alpha virus that mimics RA in its clinical presentation.

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Inflammatory Ocular Disease in US Veterans

A retrospective review of 1285 US male veterans showed the prevalence of inflammatory eye disease to be 2%. Uveitis was most common (most being anterior uveitis), followed by keratitis, scleritis, episcleritis, and acute ischemic optic neuropathy.

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The History of Citrullination

1998 marked the introduction of citrulline as a unique target in the pathogenesis of rheumatoid arthritis. The hallmark article by Schellekens et al in the Journal of Clinical Investigation has since been cited over 500 times.  Dr.

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Focus on Fatigue?

Fatigue is not far behind pain as the complaint that affects the quality of life in numerous rheumatic and autoimmune disorders. But do we need to focus on fatigue in our disease management?

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NICE Judges Apremilast Less Cost Effective than TNF Inhibitors

The National Institute for Heath and Care Excellence has turned down Otezla for coverage under the U.K. healthcare system for psoriatic arthritis.

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High Lupus Flare and Complication Rates in Lupus Pregnancy

An incident cohort study from Denmark showed that 84 SLE pregnancies resulted in 62 live births.  Lupus disease activity strongly influenced maternal complications seen in half and fetal complications were observed in one-third of cases.

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Conservative Equals Surgical Management of Lumbar Spinal Stenosis

A randomized controlled trial of compared the outcomes of  surgical decompression or physical therapy in 169 lumbar spinal stenosis patients.  After two years, intention-to-treat analyses revealed no difference between groups.

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