Articles By Kristen Demoruelle, MD

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Lung Involvement in Pre-RA

By Kristen Demoruelle, MD

When I see patients with RA-associated ILD, I’m often asked: “Are the lungs and joints really connected?” The answer is yes, and the connection extends further back than some may realize. While RA is defined by inflammation of the joints, extra-articular complications of the lung are well recognized. ILD has often been viewed as a complication of longstanding RA, but it can also appear before joint disease in a subset of patients.

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  • Kristen Demoruelle, MD

  • Dr. Demoruelle is an Associate Professor in the University of Colorado Division of Rheumatology. She is a physician-scientist with a research program that focuses on understanding how immune dysregulation in the lung, particularly mucosal autoantibody generation and neutrophil extracellular trap (NET) formation, may contribute to the development of rheumatoid arthritis (RA), RA-associated interstitial lung disease (RA-ILD), and sex differences in the development of RA.

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