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The striking propensity for gout flares to initiate at night has been recognised for centuries. In 1683, Thomas Sydenham famously observed that the typical patient "goes to bed and sleeps in good health" only to be awakened around 2:00 AM by excruciating pain.
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Dr Raewyn Poulsen is a Senior Lecturer in the Department of Pharmacology and Clinical Pharmacology at the University of Auckland, Auckland, Aotearoa/New Zealand. She is a cellular and molecular biologist studying the mechanisms involved in pathogenesis of arthropathies including osteoarthritis and gout.
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