Articles By Richard J. Johnson, MD

kidneys

The Marriage between Gout and the Kidney

By Richard J. Johnson, MD

While the link between uric acid and gout was first described by Alfred Baring Garrod in the 1800s, the proof that uric acid might actually be the cause had to await the self-experimentation of two rheumatologists from the University of Pennsylvania. Given some comments that the presence of urate crystals in synovial fluid might just be a bystander phenomenon, they decided to inject monosodium urate crystals in one knee and water in the other, and both suffered severe attacks of gout in the urate crystal injected knee.

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  • Richard J. Johnson, MD

  • Richard J, Johnson is an Emeritus Professor of Medicine from the University of Colorado at the Anschutz Medical Campus. He is both a kidney specialist and scientist.  He has a longstanding interest in gout and kidney disease, and is highly cited, with over 800 peer reviewed publications.

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