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"Patients were eligible for inclusion if they had received a diagnosis of RA (for ≥6 months), had received methotrexate (for ≥12 weeks) and experienced treatment failure of at least 1 csDMARD (including methotrexate)" citation from the paper. So, study addressing a non-naive, stablished (mean (SD) duration of RA=8.7(7.4)) RA population.....