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Don, I tooscratched my head on this. But in reading the article, I initially thought these injx were the same as our intraarticular injection - but they are not. You are correct that IA is more reliable and effective. But the point of doing infrapatellar fat pad injection is to minimize the steroid effects on articular cartilage - which this study proved, but also proved that it was not effective in managing OA knee pain. The other limitation of this study is that these were "inflammatory Knee OA" patients. Such patients (or their categorization) is another can of worms, meaning harder to identify, treat and prove benefit. Thanks for the thoughtful points! JC

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