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Stills,continuum

Treating Refractory Still's Disease

Jack Cush, MD

A full read systematic review article examined treatment options for difficult to manage systemic juvenile idiopathic arthritis, or Still’s disease.

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Vitamin D and Lupus Outcomes (11.21.2025)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com.

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Pulse Steroids and Mycophenolate in Juvenile Dermatomyositis

Jack Cush, MD

JAMA Dermatology has published a pilot study demonstrating the safety and efficacy of intermittent intravenous methylprednisolone pulse (IVMP) therapy plus mycophenolate in 28 patients with juvenile dermatomyositis (JDM).

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Cush and Kavanaugh

ACR 2025 Rheumatology Round Up

Jack Cush, MD

Drs. Jack Cush & Arthur Kavanaugh, two of rheumatology’s most trusted voices, provide a breakdown of the latest breakthroughs and hottest topics in rheumatology from the 2025 ACR Convergence meeting in Chicago.

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psoriasis,arms,pain

IL-23 Blockade Goes Oral

Aurelie Najm, MD, PhD

A new player is entering the IL-23 arena — and it’s a tablet! Icotrokinra (ICO), a first-in-class peptide that binds and blocks the interleukin-23 receptor (IL-23R), is showing encouraging efficacy and safety across a range of psoriasis (PSO) and psoriatic disease (PsD) studies.

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woman,doctor,stress,burnout,headache,HA

Stress Raises the Risk of Psoriasis

EurekAlert!

New longitudinal research reveals that severe stress caused by changes in family structure like divorce or separation experienced during the first year of life may triple the risk of developing psoriasis later in life.

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Bad Actor Cofactor (10.17.2025)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports, discusses pediatric reports, pregnancy data, diet and nutrition and more.

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Pulse Steroids and Mycophenolate in Juvenile Dermatomyositis JAMA Dermatology has published a pilot study demonstrating the safety and efficacy of intermittent intravenous methylprednisolone pulse (IVMP) therapy plus mycophenolate in 28 patients with JDM. https://t.co/i2HBycbWY9
Dr. John Cush RheumNow ( View Tweet)
A 15-year-old girl has short stature and the hand finding shown . Labs show ↓Ca²⁺, ↑PO₄³⁻, ↑PTH. What is the most likely diagnosis? https://t.co/afPUeaqfZT

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Dr. Nikhil Agrawal DrNikhilMD ( View Tweet)
So what's been tried for ICANS, knowing that it's unlikely that one therapy will fix all of it? @CarolineDiorio @ChildrensPhila in the #ACR25 BCRC pre-meeting @RheumNow https://t.co/10wdkrH29s

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David Liew drdavidliew ( View Tweet)
@CarolineDiorio @ChildrensPhila @RheumNow Indeed, there are a lot of familiar HLH/MAS friends in the post-CAR-T CRS mix... (indeed, rheum friends from many places) @CarolineDiorio @ChildrensPhila in the #ACR25 BCRC pre-meeting @RheumNow https://t.co/OzWu3MV1FA

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David Liew drdavidliew ( View Tweet)
What dictates how severe CRS is following CAR-T? (Often the critical question, and will especially be in the autoimmune space, where CAR-T is largely less time-critical) @CarolineDiorio @ChildrensPhila in the #ACR25 BCRC pre-meeting @RheumNow https://t.co/u0w4lx7YVn

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David Liew drdavidliew ( View Tweet)
@CarolineDiorio @ChildrensPhila eloquently told the #ACR25 BCRC pre-meeting about the lessons they've learned about CRS and ICANS, the major CAR-T toxicities. Many questions still to answer, but they've also understood a lot we can learn from. @RheumNow https://t.co/Jhk1eCLpD4

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David Liew drdavidliew ( View Tweet)
kids w 👇 Undifferentiated #systemic #autoinflammatory #disease Rx #IL1i N=33 =boys &girls 3.5 yrs Sx Abst#2151 #ACR25 @ACRheum @RheumNow There are many periodic fever syndromes 🤔some mutations are not yet discovered Access to &use of Anakinra canukinumab Rilonacept https://t.co/IyTx0nFxKC

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Janet Pope Janetbirdope ( View Tweet)
This cohort study from Ontario of 🚺w/axSpA ✳️GDM, antepartum hem, SMM (severe maternal morbidity) -⬆️ in axSpA ✳️Neonat complications-preterm birth Factors assoc w/SMM- age, comorbidity, gestational age at delivery Better strategies for maternal care #ACR25 @RheumNow Abs2200 https://t.co/LrVzJLnvWe

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sheila RHEUMarampa ( View Tweet)
Low percentage of glycosylated Ferritin was more specific for Stills disease but not used frequently in clinical practice. @RheumNow #ACR25 https://t.co/wTK1eIcSKX

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Bella Mehta bella_mehta ( View Tweet)
AOSD And sJIA aren't the same disease!!!. Another take on this by Scott Canna..because the clinical syndrome might have somethings distinct!! #acr25 @RheumNow

Bella Mehta bella_mehta ( View Tweet)

Bad Actor Cofactor (10.17.2025) Dr. Jack Cush reviews the news and journal reports, discusses pediatric reports, pregnancy data, diet and nutrition and more https://t.co/zDDLwwRSy9 https://t.co/2S8jPOY0Be

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Dr. John Cush RheumNow ( View Tweet)
CONGRATULATIONS: Dr. Lauren Henderson has been awarded the Gale & Ira Drukier Prize in Children’s Health Research. Lauren is a pediatric rheum at Boston Children’s Hospital, focused in difficult JIA. She has studied T-B cells interactions & long-term joint damage in JIA https://t.co/uYWrh0oasy
Dr. John Cush RheumNow ( View Tweet)
MSK Manifestations in Pediatric IBD Arthritis and musculoskeletal (MSK) symptoms may accompany pediatric-onset inflammatory bowel diseases (pIBD) as an extra-articular intestinal manifestation, but may vary in presentation and clinical course. https://t.co/VoU3itr0EM https://t.co/ar19JdrsHH

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Dr. John Cush RheumNow ( View Tweet)
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