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Long-Term Use of NSAIDs Linked to Lower Dementia Risk
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MedPage Today
Long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) was tied to a decreased risk of dementia, data from the prospective Rotterdam Study showed.
Read ArticleHydroxychloro-King (3.7.2025)
Dr. Jack Cush reviews the news, journal reports and regulatory actions from the past week on RheumNow.com
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Metanalysis of 376 studies, 347 468 pts w/ chronic pain (mean 51yrs; 70%F) finds ~40% had clinically significant depression and anxiety (more common in Women, younger people, pts w nociplastic pain). Depression common in FM (54%) & OA/RA (~28%). https://t.co/s1tcgC3y7k https://t.co/NCxkOA82jD
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MMWR: Idiopathic Pulmonary Fibrosis Mortality in the United States
Idiopathic pulmonary fibrosis (IPF), a progressive lung disease characterized by scarring and worsening lung function, has a poor prognosis. An estimated 21% of IPF deaths might be attributable to occupational… https://t.co/FQpotKrgzR https://t.co/hruzwcD1E6
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ED Utilization by Psoriatic and Spondyloarthritis Patients
A cohort analysis of ambulatory ED utilization by patients with PsA and r-axSpA demonstrated significant use for less urgent and nonurgent health issues, particularly in rural settings.
https://t.co/Pl9k3GN0mp https://t.co/kI1rOue9ws
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Intraarticular Steroids in OA Lowers Need for Pain Meds
Is it possible that intra-articular corticosteroid injections for osteoarthritis might affect the use of opioids?
https://t.co/qkTN7CpuMZ https://t.co/npuT88Sj2m
Dr. John Cush RheumNow ( View Tweet)

Hydroxychloroquine and Sjögren's - despite widespread use, there is not good data showing HCQ efficacy in Sjogrens. Although safe and may lower Ig levels - 3 RCTs found no clinical benefit, but retrospective & open-label studies did https://t.co/8l1gZoKqFA https://t.co/JNGmpnNMHx
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Early Hydroxychloroquine Slows Cutaneous Lupus Progression
A prospective study of patients with limited cutaneous lupus erythematosus (CLE) shows that early introduction of hydroxychloroquine (HCQ) may prevent progression to systemic lupus erythematosus (SLE).… https://t.co/evsvf2GQiL https://t.co/J0Zl35FEHz
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Bimekizumab efficacy and safety in patients with psoriatic arthritis who had skin and nail psoriasis at baseline: Up to 2-year results from two phase 3 studies
https://t.co/QGdQtp3Mbe
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"Never doubt that a small group of thoughtful, committed citizens can change the world; indeed, it's the only thing that ever has."
- Margaret Mead
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Full read review of Hydryoxychloroquine -its pharmacology, MOA (eg, blocking TLR 7 & 9), Dz specific efficacy and adverse effects https://t.co/N7XVbfnsfi https://t.co/yjKwcfugOJ
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Bubble Trouble - When Bullous Lupus Bursts onto the SLE Scene
Presentation by Dr. Alana Haussmann at the Rheumatology Winter Clinical Symposia - Feb 2025
https://t.co/N4u4AUbdqH https://t.co/PotKfpOkH7
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Available the first time: https://t.co/4UQlqwujiR 2025 On Demand!
On Demand gives you access to all lectures, Q & A panels, and STEP talks, and all speaker slides and handouts — all packed with insights you won’t find anywhere else.
Non-CME, practical, and finally here.… https://t.co/MHFUWb3az1 https://t.co/cqzZG40Xp5
Links:
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An Unusual Consult for Myopathy
Presentation by Dr. Kelsey Lemmen, at the Rheumatology Winter Clinical Symposia - Feb 2025
https://t.co/DYlzee6qcs https://t.co/nUxTC9roF9
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A Review of Relapsing Polychondritis
A current review in the Journal of Thoracic Disease on relapsing polychondritis (RP), suggests that while this rare disorder may have an uncertain pathogenesis, its diagnosis and therapeutical management has improved.… https://t.co/keacvqjlU7 https://t.co/TkYwNnYtxF
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Crohn’s Microbiome may Predispose to Axial Spondyloarthritis
Researchers at Weill Cornell Medicine found that people with Crohn’s disease and related joint inflammation have distinct gut bacteria, with Mediterraneibacter gnavus as a potential biomarker.
https://t.co/SI03wAJ3UU https://t.co/dlt3VxBDLw
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CDC: More women (25.4%) than men (23.2%) had chronic pain in last 3 mos, Esp in large central metropolitan areas(22% vs 19%, F>M). For both recent chronic pain increased with decreasing urbanicity. https://t.co/rDsCQWvAae https://t.co/mhczpWFsdw
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Neuropsychiatric Lupus: More than just a headache
Presentation by Dr. Daniel Carlson, at the Rheumatology Winter Clinical Symposia - Feb 2025
https://t.co/v0da4UNFNV https://t.co/BhBKOgak4W
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Normalizing Serologies Enhances Remission in SLE
Analysis of five phase III belimumab (BEL) trials reveals that normalizing serologies affords protection against severe and renal SLE flares, supporting the concept of treat-to-target to minimize risk in SLE.… https://t.co/eW9EUyvts7 https://t.co/OdM0WkLtjd
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Intraarticular Steroids in OA Lowers Need for Pain Meds
Is it possible that intra-articular corticosteroid injections for osteoarthritis might affect the use of opioids?
https://t.co/pw6vWbFRQx https://t.co/5KrB9uJv7M
Dr. John Cush RheumNow ( View Tweet)