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Stop Counting Bugs (10.4.2024)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.This week’s rants include the microbiome, PsA treatment choices and fishing for P-values in research.

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Using MRI to Evaluate Knee Pain

MedPage Today

Interim results from a randomized trial show that middle-aged patients with knee pain and suspected meniscal tears can benefit from MRI scans even in relatively simple cases.

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Declining Menopausal Hormone Therapy in Postmenopausal Women

Jack Cush, MD

A two decade cross-sectional population study has shown a marked downward trend in menopausal hormone therapy (MHT), with an over 80% reduction, especially in women aged 52 - 65 years.

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I Can't Treat Ugly (9.20.2024)

Jack Cush, MD

Dr. Jack Cush reviews the news, journal articles and a new FDA approval for EGPA, this week on the Podcast.

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Conservative Treatment of Acute Vertebral Fractures

Jack Cush, MD

A network meta-analysis of pain outcomes in patients with acute osteoporotic vertebral compression fractures (VCFs) showed short-term success with calcitonin and NSAIDs in decreasing pain during activity, but long-term benefits were superior for teriparatide compared to bisphosphonates.

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A Family History of Arthritis?

Jack Cush, MD

Using data from the population based All of Us (AoU) Research Program, a self reported history of arthritis and related conditions was associated with an increased risk for arthritis, osteoporosis, and carpal tunnel syndrome.

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Romosozumab vs. Teriparatide in Postmenopausal Osteoporosis

Jack Cush, MD

The effectiveness and safety of romosozumab (ROMO) and teriparatide (TPTD) were compared in a clinical setting, and ROMO showed greater increases in BMD than TPTD after 12 months of therapy, along with a higher completion rate.

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Lead with Lupus (8.2.2024)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com - leading with lupus because everyone wants to know about lupus!

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knee.calcinosis.inflammation

Frequency and Features of CPPD

Jack Cush, MD

An international cohort study of patients with calcium pyrophosphate deposition (CPPD) disease, i.e., recurrent acute CPP crystal arthritis, chronic CPP crystal inflammatory arthritis, and crowned dens syndrome (CDS) identifies both acute and chronic inflammatory phenotypes, each with distinctive clinical and imaging diagnostic features.

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Pollution and Autoimmunity (7.12.2024)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.

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ICYMI: 2023 EULAR Non-pharmacological Management of Hip and Knee Osteoarthritis: 2023 update

Jack Cush, MD

EULAR has published the 2023 updated recommendations for the optimal non-pharmacological management of hip and knee osteoarthritis (OA).

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Using MRI to Evaluate Knee Pain Interim results from a randomized trial show that middle-aged patients with knee pain and suspected meniscal tears can benefit from MRI scans even in relatively simple cases. https://t.co/xAVA07LcqD https://t.co/YRrZgiMQjs

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Dr. John Cush RheumNow ( View Tweet)
40 postmenopausal F Rx w/ Blackcurrant (BC) vs PBO. @6 mos BC lowered IL-1β (P .056) & RANKL (P .052) & BMD inversely correlated w/ RANKL change. BC bone protective may also be through enhancing gut microbial balance https://t.co/wy9VR3fwvJ https://t.co/cRCjSb5XDQ

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Dr. John Cush RheumNow ( View Tweet)
Retrospective Taiwan's Health claims: studied 6408 RA pts, half HCQ users vs non-users. No higher risk of osteoporosis in HCQ users vs non-users (aHR=0.99; 95% CI: 0.82–1.196). Why study this? HCQ may suppress both bone formation/resorption https://t.co/xShLXMElnH https://t.co/lkvihaYuAd

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Dr. John Cush RheumNow ( View Tweet)
A Family History of Arthritis? Using data from the population based All of Us Research Program, a self reported history of arthritis and related conditions was associated with an increased risk for arthritis, osteoporosis, and carpal tunnel syndrome. https://t.co/SApbPLHquQ https://t.co/hOamnYyRoz

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Dr. John Cush RheumNow ( View Tweet)
Elder adult Cohort study of 2413 women & 792 men w/ hip BMD-defined osteoporosis based on CT scans, shows 30% of women & 34% of men had hip Fx. Rx w/ alendronate (34%F; 24% M) signif lowered Fx rates (aOR 0.26 and 0.21, respectively) = no sex difference https://t.co/briuZAYVKx https://t.co/xrZ12TmMvM

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Dr. John Cush RheumNow ( View Tweet)
Most read at Annals: Pharmacologic Treatment of Primary #Osteoporosis or Low Bone Mass to Prevent Fractures in Adults: A Living Clinical Guideline From @ACPIMPhysicians https://t.co/wMg63aG4rB https://t.co/ZDKdHkH0fh

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Annals of Int Med AnnalsofIM ( View Tweet)
RT @drminidey OP0165- incidence & risk factors of D2T RA in an early RA cohort Factors assoc with D2T RA: 🩸 Seropositivity 🦴 Erosions 📈 Disease activity 📊 D2T pts have higher steroid doses & more commonly develop iatrogenic-related #comorbidities, e.g. osteoporosis

Dr. John Cush RheumNow ( View Tweet)

Late “Breaking”: Reducing Osteoporotic Fractures in Postmenopausal Women Dr. Janet Pope discusses abstract POS0583 presented at Eular 2024 in Vienna, Austria. https://t.co/HIXV4EUkJb https://t.co/p38e6pzAvC

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Dr. John Cush RheumNow ( View Tweet)
When would I use #Aclasta vs #Prolia since #denosumab has LESS #fractures ▶️younger women with #osteoporosis requiring Rx due to long safety ▶️less wearing off when stopping it ▶️noncompliant Pts as prolia reverses effect when dose is missed @RheumNow #EULAR2024 @eular_org https://t.co/0RTGx0sCTd

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Janet Pope Janetbirdope ( View Tweet)

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