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Lower TNF Inhibitor Persistence in Spondylitis

d Jack Cush, MD

A claims data analysis shows that only one-third of ankylosing spondylitis (AS) treated with tumor necrosis factor inhibitors (TNFi) therapy remain on their initial drug in the 2 years post initiation.

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First Line IL-1 Inhibition in Systemic JIA

d RheumNow

First-line treatment of systemic juvenile idiopathic arthritis (JIA) with anakinra (Kineret) was highly effective as monotherapy, minimizing the need for glucocorticoids, a single-center prospective study found.

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EULAR Consensus Guidelines for Juvenile Localized Scleroderma

d Jack Cush, MD

A EULAR international committee of 15 experts in pediatric rheumatology have established consensus-based recommendations for the management of juvenile localised scleroderma (JLS).

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Tramadol May be Associated with Increased Mortality in Osteoarthritis

d Jack Cush, MD

JAMA reports that tramadol use in adults with osteoarthritis (OA) may be associated with increased all-cause mortality (compared with nonsteroidal anti-inflammatory drugs).

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New Sleep Medicine Guidelines for Obstructive Sleep Apnea

d Jack Cush, MD

The American Academy of Sleep Medicine (AASM) has established new guidelines for the evaluation and treatment of sleep-disordered breathing in adults, specifically guiding the use of positive airway pressure (PAP) in the treatment of obstructive sleep apnea (OSA) in adults. 

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2018 Swedish Guidelines for Giant Cell Arteritis Treatment

d Jack Cush, MD

The Swedish Society of Rheumatology has developed evidence-based guidelines for the management of giant cell arteritis (GCA) with a focus on the appropriate use of corticosteroids and tocilizumab. 

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QD Clinic - Secondary Loss of Efficacy | RheumNow - Her 1st TNFi fails after 2 years - then what? https://t.co/owAT4YZuBG

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QD Clinic - Shingles Happens | RheumNow - How to prevent and manage Shingles https://t.co/pdvsvuzcsd

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Dr. John Cush RheumNow ( View Tweet)

GSK has issued a new safety warning on Benlysta with a low frequency risk of serious depression & suicidal ideation; new data added to PI based on new 4003 SLE pt trial with Suicidal ideation seen in 0.7% on BEL and 0.2% on PBO; depression (0.3% vs <0.1%) https://t.co/cMp52MLKxs

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You can attend RheumNow Live for Free via online access - Innovative lectures and Q&A Panels beginning friday afternoon 3/22, ending Sunday 3/24. Register for FREE at https://t.co/lbrJ0Dp1Hb

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Study of 1021 Scleroderma patients from the EUSTAR cohort shows progressive skin fibrosis (>5 mRSS in 1 yr) was associated with significant lung function decline (FVC worse ≥10% (53.6% vs 34.4%; p<0.001) and all-cause mortality (15.4% vs 7.3%; p=0.003). https://t.co/VNX3rF1LUH

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Osteoarthritis Initiative shows weight loss (>5% BMI) in obese and overweight persons resulted in a lower risk of knee cartilage loss assessed by MRI after 8 yrs; results only seen in diet only or diet + exercise pts. https://t.co/0S75xrfONk

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Dr. John Cush RheumNow ( View Tweet)

24 mos results show, that in steroid treated pts, denosumab SC is superior to po risedronate at increasing spine and hip bone mineral density (BMD); adverse events and Fracture rates were similar in both groups https://t.co/vSBlF4uBXa

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Dr. John Cush RheumNow ( View Tweet)

23 year followup of the COBRA trial shows that early aggressive treatment with SSZ or combination + Tapered prednisone yields a long term survival equal to the general population; thereby negating RA potential to incr mortality https://t.co/bLR8k5eZ9h

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Dr. John Cush RheumNow ( View Tweet)

QD Clinic - Biologic Class Switching | RheumNow - Can you switch biologics within the same class? Heck yeah! https://t.co/ybHEF6Cbp5

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Dr. John Cush RheumNow ( View Tweet)

CORRONA Registry - Chronic opioid use doubled 2002-2015, rising from 7.4% to 16.9%. Strongest predictors included severe pain (HR 2.53), antidepressant use (HR 1.79), high Dz activity (HR 1.55) & high disability (HR 1.45). https://t.co/vPBqvWIy19

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Dr. John Cush RheumNow ( View Tweet)

Full Read Review Inclusion Body myositis: IBM) is slowly progressive & commonly misdiagnosed as arthritis or polymyositis. IBM is assoc w/ CV complications and other autoimmune dz. Look for unique features such as finger flexor and knee extensor weakness. https://t.co/WteGovZBFL

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Dr. John Cush RheumNow ( View Tweet)

Free online access to RheumNow Live - 16 hrs of Innovative lectures and Q&A Panels beginning friday afternoon 3/22, ending Sunday 3/24. Register for FREE at https://t.co/wIgS5rq4UE or come to https://t.co/4UQlqwujiR

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Dr. John Cush RheumNow ( View Tweet)

PODCast of the last weeks QD Clinics can be found on iTUnes and here >> https://t.co/6SJHvbA2ho

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Dr. John Cush RheumNow ( View Tweet)

A 10-year study of more than half a million Danish children found no evidence that vaccines increased the risk of autism. The study comes at a time when anti-vaccine suspicion is on the rise again. https://t.co/ZhZaW1kUQl

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NYT Health NYTHealth ( View Tweet)

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