All News

heart.EKG_.CVD_.jpg

FDA Slaps a Boxed Warning on Febuxostat for CV Risk

d Jack Cush, MD

The U.S. Food and Drug Administration (FDA) has reviewed data from the Cardiovascular Safety of Febuxostat and Allopurinol in Patients with Gout and Cardiovascular Morbidities (CARES) trial and concluded there is an increased risk of death with Uloric (febuxostat) compared with allopurinol, and has added this as a boxed warning to the drug’s product label.

Read Article
TB.EMimage.CDC_.jpg

The Risk of Tuberculosis with TNF Inhibitors

d Jack Cush, MD

A study from Turkey shows that among 2117 patients treated with a TNF inhibitor (TNFi) the risk of developing TB was 6 fold higher in those treated with a TNFi compared to non-users.

Read Article
RN.podcast.resized.jpg

RheumNow Podcast - Death and Surgery (2-22-19)

d Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com:

Read Article
microbio2.jpg

Lupus Microbiome May Drive Disease Activity

d Jack Cush, MD

Silverman and colleagues have published their study of the fecal microbiome of systemic lupus erythematosus (SLE) patients and found roughly five times more gut bacteria known as Ruminococcus gnavus, and that these abnormalities in microbiota can correlate with measures of disease severity i

Read Article
injection_1.jpg

Impressive Survival of Interleukin-1 Inhibitors in Systemic Juvenile Idiopathic Arthritis

d Jack Cush, MD

The drug retention rate of interleukin-1 inhibitors (IL-1) used to treat systemic juvenile idiopathic arthritis (JIA) appears to be quite high according to a new study. 

Read Article
DVT.PE_.Blood_.jpg

Safety Warnings for Higher Dose Tofacitinib

d Jack Cush, MD

Pfizer has issued a press release regarding the safety of tofacitinib, citing higher rates of pulmonary embolism and death associated with the use of higher dose tofacitinib 10mg bid in rheumatoid arthritis (RA) patients treated in a long-term safety trial.  

Read Article
Taiwanese insurance claims data study shows that Sjogrens syndrome patients (n=13398) have increased risk of osteonecrosis of jaw compared to 54K controls (0.08%vs0.03%, p=0.017) & also bisphosphonate ONJ (adjusted HR=7.9, p<0.001). https://t.co/qQSV16muNN

Links:

Dr. John Cush RheumNow ( View Tweet)

JAMA reports from 2005-2015 PCP density in USA decreased from 46.6 to 41.4 per 100 000, with greater losses in rural areas. Every 10 PCP increase per 100K was assoc w/ added 51 day survival; every 10 specialists per 100k correlated with 19d incr survival https://t.co/81TRwFzOnH

Links:

Dr. John Cush RheumNow ( View Tweet)

The Johns Hopkins Myositis Center is proud to announce the launch of the Peter Frampton Myositis Research Fund. https://t.co/SAVf1AEdqO Join @peterframpton and our Myositis Center team as we work to improve the lives of those impacted by #myositis https://t.co/BjOOaHYuJq

Links:

Johns Hopkins Rheumatology jhrheumatology ( View Tweet)
QD Clinic Week 6 Podcast - case based lessons from the real world. Discusion of Pregnancy Rules, Optimizing MTX, Changing DMARDs, Stopping Anakinra in Still's, NP decisions. Listen on iTUNES or Here https://t.co/61KO2jKxJp

Links:

Dr. John Cush RheumNow ( View Tweet)

RheumNow Podcast is up! Discussions of Death rates, Jt. Surgeries, Lupus microbiome & activity, JIA outcomes, Tofacitinib Warnings, 25 Yr Hip replacements. Watch here https://t.co/tYS6WDV3in or Listen to the Podcast on iTunes or soundcloud https://t.co/NkXngajhUB

Links:

Dr. John Cush RheumNow ( View Tweet)

For SLE and other pts with photosensitive skin dz: FDA updated regulations for sunscreens—ONLY zinc oxide and titanium dioxide are Generally Recognized As Safe and Effective (GRASE); combo sunscreen-insect repellents are a big NO! https://t.co/KuaJcT6g1s @RheumNow

Links:

k dao KDAO2011 ( View Tweet)

FDAhas added a boxed warning to the label for gout drug febuxostat (Uloric) based on results of a large postmarketing safety study and AAC panel Recs. FDA concluded that there is an increased risk for death with febuxostat compared allopurinol https://t.co/v1ANA3lI0g

Links:

Dr. John Cush RheumNow ( View Tweet)

QD Clinic - Rules for Pregnancy | RheumNow - Share this video A patient on a biologic wants to get pregnant... https://t.co/DhdFLFAR0O

Links:

Dr. John Cush RheumNow ( View Tweet)

A genuine way to engender trust at each visit, is to inquire about something important to the patients life. More impactful, is when you spend time answering, suggesting, guiding them on important health matters not theirs (like sick husband in hospital, death in family, etc)

Dr. John Cush RheumNow ( View Tweet)

The Best Rheums go to the Best Meetings - RHEUMNOW LIVE - March 22-24 2019 Great Fort Worth, TX - Short Lectures, interactive sessions, Q&A panels, TED (like) Talks, digital, streaming and much more. You dont want to miss this meeting! https://t.co/5TVg0Frsbf

Links:

Dr. John Cush RheumNow ( View Tweet)

QD Clinic - When to Stop Anakinra | RheumNow - A Stills patient wants to stop his anakinra - but when is the right time? https://t.co/aI3f6D3mwX

Links:

Dr. John Cush RheumNow ( View Tweet)

QD Clinic - The NP Says the Patient is Flaring | RA patient is Flaring with interruption of Abatacept; the NP want to know what to do. https://t.co/IVhbWwjWrS

Links:

Dr. John Cush RheumNow ( View Tweet)

Check out these cool case presentations from #RWCS2019 Fellows. https://t.co/xJifZ7zXYQ

Links:

Dr. John Cush RheumNow ( View Tweet)

Swedish Population study shows a 2 fold higher mortality in patients with RA and MSK (SMR 2.2 & 1.5) patients with < 9 years of education compared with those with > 12 years of education. https://t.co/bjil9FAe4I

Links:

Dr. John Cush RheumNow ( View Tweet)

Do you get our email newsletter?

Looking for the latest rheumatology news & trends? Sign up for the RheumNow weekday newsletter:

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Rheumnow.com is a news source dedicated to the field of Rheumatology. It is written by experts in the field, and written for rheumatologists and individuals working in related fields. Rheumnow.com provides daily updates on the site and in your inbox when you are signed up for our newsletter.

Copyright 2024 All Rights Reserved.

×